Mirakhur R K
Department of Anaesthesia, Queens University of Belfast.
J R Soc Med. 1991 Aug;84(8):481-3. doi: 10.1177/014107689108400811.
A survey has been carried out amongst the UK based members of the Association of Anaesthetists of Great Britain and Ireland regarding their practice of premedication. Ninety-three per cent of respondents (reply rate 51.7%) used sedative-hypnotic premedication routinely in adults and 84% in children. However, anticholinergic premedication was used by only 36% in adults and 56% in children. Temazepam was the most frequently used sedative premedicant in adults and trimeprazine in children. Atropine and hyoscine were the most frequently used anticholinergic drugs. The main reasons for using sedative-hypnotic premedication were allaying anxiety and providing sedation. The main reasons for using anticholinergic drugs were drying of secretions and protection against vagal overactivity. This survey concludes that while sedative-hypnotic premedication continues to be used in the majority of patients with oral benzodiazepines the most frequently used drugs, the use of anti-cholinergic premedication continues to decline.
针对英国和爱尔兰麻醉医师协会在英国的成员进行了一项关于其术前用药实践的调查。93%的受访者（回复率51.7%）在成人中常规使用镇静催眠类术前用药，在儿童中这一比例为84%。然而，成人中仅36%使用抗胆碱能术前用药，儿童中为56%。替马西泮是成人中最常用的镇静术前用药，而儿童中是异丙嗪。阿托品和东莨菪碱是最常用的抗胆碱能药物。使用镇静催眠类术前用药的主要原因是减轻焦虑和提供镇静作用。使用抗胆碱能药物的主要原因是减少分泌物和预防迷走神经活动过度。这项调查得出结论，虽然大多数患者仍继续使用口服苯二氮䓬类药物作为最常用药物进行镇静催眠类术前用药，但抗胆碱能术前用药的使用仍在持续减少。
