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儿科麻醉中的抗胆碱能药物。1990年芬兰现状调查

Anticholinergic drugs in paediatric anaesthesia. A survey of their present position in Finland 1990.

作者信息

Rautakorpi P, Ali-Melkkilä T, Kanto J

机构信息

Loimaa District Hospital, Finland.

出版信息

Ann Chir Gynaecol. 1994;83(1):64-8.

PMID:8053641
Abstract

A survey regarding the present use of anticholinergic drugs in paediatric patients was carried out amongst anesthetists in Finland. Out of a total of 430 questionnaires 229 were returned after two mailings, giving a reply rate of 53%. Fourty-nine percent of the responders used these drugs routinely in premedication in 1990, while 55% were using them in 1985. In various age groups anticholinergic premedication was given most often to patients aged 0-1 year. The procedures in the airway region and eye surgery were the main indications for the preanaesthetic use of anticholinergic drugs while reflex bradycardia was the most frequent indication for administering these drugs during the perioperative period. Atropine and glycopyrrolate were the most popular drugs and the principal route of administration was intravenously, just before induction of anaesthesia. Glycopyrrolate with neostigmine was the most popular combination when the competitive neuromuscular block was reversed. It is concluded that almost half of the Finnish anaesthetists give anticholinergic premedication to children routinely and the position of anticholinergic drugs in paediatric anaesthesia has changed only a little during the last few years.

摘要

芬兰的麻醉师对儿科患者抗胆碱能药物的当前使用情况进行了一项调查。在总共430份问卷中,经过两次邮寄后共收回229份,回复率为53%。1990年,49%的受访者在术前用药中常规使用这些药物,而在1985年这一比例为55%。在各个年龄组中,0至1岁的患者接受抗胆碱能术前用药的情况最为常见。气道区域手术和眼科手术是麻醉前使用抗胆碱能药物的主要指征,而反射性心动过缓是围手术期使用这些药物最常见的指征。阿托品和格隆溴铵是最常用的药物,主要给药途径是在麻醉诱导前静脉注射。在逆转竞争性神经肌肉阻滞时,格隆溴铵与新斯的明联用是最常用的组合。得出的结论是,几乎一半的芬兰麻醉师常规给儿童使用抗胆碱能术前用药,并且在过去几年中抗胆碱能药物在儿科麻醉中的地位变化不大。

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