Mirakhur R K, Clarke R S, Dundee J W, McDonald J R
Anaesthesia. 1978 Feb;33(2):133-8. doi: 10.1111/j.1365-2044.1978.tb08340.x.
A survey was carried out amongst anaesthetists in the United Kingdom and Ireland regarding the use of anticholinergic drugs. Sixty-two per cent of these anaesthetists use these drugs routinely in premedication. The drugs are nearly always atropine or hyoscine and are used mainly for reducing secretions and protection against vagal stimulation. A longer-acting drug was desired by 22% and 60% would like to use an orally effective anticholinergic drug. Though quite a number of minor side effects are high-lighted, the majority do not consider these serious enough to stop routine use. There is now a tendency amongst many anaesthetists either not to use these drugs routinely or use them less often, more rationally and in reduced dosage.
针对英国和爱尔兰麻醉师使用抗胆碱能药物的情况开展了一项调查。这些麻醉师中有62%在术前用药时常规使用这些药物。这些药物几乎总是阿托品或东莨菪碱,主要用于减少分泌物以及预防迷走神经刺激。22%的人希望有一种作用时间更长的药物,60%的人希望使用口服有效的抗胆碱能药物。尽管有相当多的轻微副作用被提及,但大多数人认为这些副作用不足以严重到停止常规使用。现在,许多麻醉师倾向于要么不常规使用这些药物,要么减少使用频率,更合理地使用并降低剂量。