Kawai K, Kawai K, Konishi K, Kishimoto S, Kanemitsu K, Kamei N, Obayashi H, Okada T, Konishi H
Kyoto Prefectural University of Medicine.
Nihon Hifuka Gakkai Zasshi. 1991 Mar;101(4):415-20.
Recently secretory IgA (S-IgA) was found to be secreted from the eccrine gland. By using a sandwich enzyme immunoassay, we measured the concentration of S-IgA 1) in sweat (sweat S-IgA) and 2) in the extract buffer obtained by pipetting++ on the skin (skin surface S-IgA). Skin surface hydration and skin surface lipid were measured at the sites where the samples of skin surface S-IgA were collected. (These measurements were taken immediately after the buffer was pipetted). The quantity of both sweat S-IgA and skin surface S-IgA differed according to the sites where they were collected. Sites in order of decreasing sweat S-IgA level: face, chest, forearm. Sites in order of decreasing skin surface S-IgA level: face, chest, palm, forearm, sole. (Skin surface S-IgA levels on palm and forearm were approximately equal). Although the amount of skin surface S-IgA was not related to the skin surface hydration, there was a significant correlation between skin surface S-IgA and skin surface lipid.
最近发现外分泌腺可分泌分泌型免疫球蛋白A（S-IgA）。我们采用夹心酶免疫测定法，测定了1）汗液中S-IgA的浓度（汗液S-IgA）以及2）通过在皮肤上移液++获得的提取缓冲液中S-IgA的浓度（皮肤表面S-IgA）。在采集皮肤表面S-IgA样本的部位测量皮肤表面水合作用和皮肤表面脂质。（这些测量在移液缓冲液后立即进行）。汗液S-IgA和皮肤表面S-IgA的量根据采集部位的不同而有所差异。汗液S-IgA水平由高到低的部位依次为：面部、胸部、前臂。皮肤表面S-IgA水平由高到低的部位依次为：面部、胸部、手掌、前臂、脚底。（手掌和前臂的皮肤表面S-IgA水平大致相等）。虽然皮肤表面S-IgA的量与皮肤表面水合作用无关，但皮肤表面S-IgA与皮肤表面脂质之间存在显著相关性。
