Gradoni L, Gramiccia M, Léger N, Pesson B, Madulo-Leblond G, Killick-Kendrick R, Killick-Kendrick M, Walton B C
Laboratorio di Parassitologia, Istituto Superiore di Sanità, Roma, Italy.
Trans R Soc Trop Med Hyg. 1991 Mar-Apr;85(2):217-9. doi: 10.1016/0035-9203(91)90027-v.
As a part of a general survey on leishmaniases and sandflies of the Maltese islands, 22 Leishmania stocks were isolated from human visceral (1) and cutaneous (1) cases, dogs (16) and sandflies (4). They were characterized by the analysis of 15 enzymes. The commonest Mediterranean L. infantum zymodeme, MON 1, was found to cause human and canine visceral leishmaniasis; L. infantum MON 78, which has so far been isolated only in Malta, was the agent of human cutaneous leishmaniasis. Both zymodemes were isolated from the same sandfly species, Phlebotomus perniciosus.
作为对马耳他群岛利什曼病和白蛉的一项综合调查的一部分，从人类内脏利什曼病（1例）、皮肤利什曼病（1例）、犬类（16例）和白蛉（4例）中分离出了22株利什曼原虫。通过对15种酶的分析对它们进行了鉴定。发现最常见的地中海婴儿利什曼原虫酶谱型MON 1可引起人类和犬类内脏利什曼病；婴儿利什曼原虫MON 78，迄今为止仅在马耳他分离到，是人类皮肤利什曼病的病原体。这两种酶谱型均从同一种白蛉——嗜人按蚊中分离得到。
