Nebozhina L V, Klitsunova N V, Tartakovskiĭ I S, Bykovskiĭ A N
Zh Mikrobiol Epidemiol Immunobiol. 1991 Jun(6):14-8.
The interaction of L. pneumophila with lymphoblastoid cell cultures H9 and H9/IIIB and epithelial cell cultures HEp-2 mutual influence have been noted. L. pneumophila penetrates into cells HEp-2 and multiplies there due the so-called "spin phagocytosis". The study of the influence of the preparations of interferon, Leukinferon and Reaferon, on the adhesive capacity of bacteria and their penetration into eukaryotic cells has revealed that the preliminary treatment of both bacteria and cells HEp-2 with the preparations of interferon prior to their infection with Legionella leads to a decrease in the number of microorganisms associated with cells.
已注意到嗜肺军团菌与淋巴母细胞样细胞培养物H9和H9/IIIB以及上皮细胞培养物HEp-2之间的相互作用。嗜肺军团菌通过所谓的“旋转吞噬作用”侵入HEp-2细胞并在其中繁殖。对干扰素制剂（白细胞干扰素和重组干扰素）对细菌黏附能力及其侵入真核细胞的影响的研究表明，在军团菌感染之前，先用干扰素制剂对细菌和HEp-2细胞进行预处理，会导致与细胞相关的微生物数量减少。
