Uchida M, Nigauri T, Shimada S, Inoue A
Dept. of Head and Neck Surgery, Cancer Institute Hospital, Tokyo, Japan.
Gan To Kagaku Ryoho. 1991 Sep;18(12):2070-6.
Today, in the treatment of oral cancer, combined resection and reconstructive surgery has shown marked progress. Especially, the surgical procedures of bone graft after mandibulectomy have been seen widespread application. In the treatment of nasopharyngeal cancer, adjuvant chemotherapy after therapeutic dose of irradiation indicates a better survival rate than radiation alone, and in advanced nasopharyngeal cancer, a wide resection is effective for cure. In the surgical treatment of hypopharyngeal cancer, by the immediate reconstruction of pharynx with jejunum, patients can eat orally in a short time. The most important problem in the treatment of head and neck cancer is development of effective chemotherapy against distant metastases.
如今,在口腔癌的治疗中,联合切除与重建手术已取得显著进展。特别是,下颌骨切除术后的骨移植手术已得到广泛应用。在鼻咽癌的治疗中,治疗剂量放疗后辅助化疗的生存率优于单纯放疗,而在晚期鼻咽癌中,广泛切除对治愈有效。在下咽癌的外科治疗中,通过空肠立即重建咽部,患者可在短时间内经口进食。头颈癌治疗中最重要的问题是开发针对远处转移的有效化疗方法。