Hoffman C, Nakamoto D, Okal R, Clochesy J M
Nurse Anesth. 1991 Sep;2(3):119-25.
Early postoperative hypoxemia may be due to a reduced functional residual capacity, hypoventilation, and ventilation-perfusion mismatch. These factors reduce the partial pressure of the arterial oxygen which ultimately reduces the oxygen transported to the tissues by decreasing the hemoglobin saturation. This may lead to cellular ischemia and death. Oxygen saturation may decrease during transport from the operating room to the postanesthesia care unit. The length of transport time in large operating suites may exceed 5 minutes, which may lead to inadequate oxygenation. This research used a pretest-posttest control group design on a convenience sample. Subjects were randomized into either the treatment or control group. At emergence, the SpO2 measured and the stopwatch started. The treatment group received 40% oxygen via a venturi mask during transport while the control group breathed room air. After a routine transport to the postanesthesia care unit, the SpO2 was again measured and the transport time was recorded. Oxygen saturation was found to be significantly greater in the group breathing supplemental O2 during transport.
术后早期低氧血症可能是由于功能残气量减少、通气不足以及通气-血流不匹配所致。这些因素会降低动脉血氧分压，最终通过降低血红蛋白饱和度减少输送到组织的氧气量。这可能导致细胞缺血和死亡。从手术室转运至麻醉后护理单元的过程中，血氧饱和度可能会降低。大型手术室的转运时间可能超过5分钟，这可能导致氧合不足。本研究采用前测-后测对照组设计，选取便利样本。受试者被随机分为治疗组或对照组。在苏醒时，测量SpO2并启动秒表。治疗组在转运过程中通过文丘里面罩接受40%的氧气，而对照组呼吸室内空气。在常规转运至麻醉后护理单元后，再次测量SpO2并记录转运时间。结果发现，转运过程中呼吸补充氧气的组血氧饱和度显著更高。
