Sia S, D'Andrea V, Mamone D, Pagnotta L, Verre M
Servizio di Anestesia e Rianimazione, Ospedale Civile A. Pugliesé, Catanzaro.
Minerva Anestesiol. 1994 Nov;60(11):657-62.
To determine the incidence of hypoxaemia and the efficacy of oxygen therapy in the early postoperative period.
Prospective, randomized study.
Regional hospital.
89 patients undergoing general anaesthesia divided into two groups, I (n = 45) and II (n = 44).
Patients of group I breathed room air while patients of group II received supplementary oxygen.
Oxygenation was monitored continuously for 60 minutes with a pulse oximeter after the end of surgery; hypoxaemia was graded into four values of SpO2: mild (86-90%), moderate (81-85%), severe (76-80%), extreme (< or = 76%). One or more episodes of mild hypoxaemia were recorded in 68% of patients in group I and in 36% of patients in group II (p < 0.005); moderate hypoxaemia were recorded in 51% of patients in group I compared with 13% of patients in group II (p < 0.001). Episodes of severe or extreme hypoxaemia were recorded in 22% and in 6% of patients in group I; no patients in group II exhibited such small values of saturation. The smallest recorded SpO2 values were 81 +/- 5.94% in group I and 89 +/- 8.63% in group II (p < 0.001).
There is a high incidence of clinically unsuspected hypoxaemia in the early postoperative period, the use of supplemental oxygen reduces but does not prevent hypoxaemic episodes, every patient should be monitored continuously with a pulse oximeter in the recovery room.
确定术后早期低氧血症的发生率及氧疗的效果。
前瞻性随机研究。
地区医院。
89例接受全身麻醉的患者分为两组，I组（n = 45）和II组（n = 44）。
I组患者呼吸室内空气，而II组患者接受补充氧气。
术后结束后用脉搏血氧仪连续监测氧合60分钟；低氧血症根据SpO₂值分为四级：轻度（86 - 90%）、中度（81 - 85%）、重度（76 - 80%）、极重度（≤76%）。I组68%的患者记录到一次或多次轻度低氧血症发作，II组为36%的患者（p < 0.005）；I组51%的患者记录到中度低氧血症发作，而II组为13%的患者（p < 0.001）。I组22%的患者记录到重度或极重度低氧血症发作，II组为6%的患者；II组没有患者出现如此低的饱和度值。记录到的最小SpO₂值在I组为81±5.94%，在II组为89±8.63%（p < 0.001）。
术后早期存在临床上未被怀疑的低氧血症的高发生率，补充氧气的使用可减少但不能预防低氧血症发作，在恢复室应对每位患者用脉搏血氧仪进行连续监测。
