Chevrolet J C, Jolliet P, Abajo B, Toussi A, Louis M
Department of Medicine, Hôpital Cantonal Universitaire, Geneva, Switzerland.
Chest. 1991 Sep;100(3):775-82. doi: 10.1378/chest.100.3.775.
Intubation and mechanical ventilation are well-established techniques in the management of patients with acute respiratory failure; however, there are situations in which these procedures cannot be used safely for various reasons. A recently described noninvasive technique, nasal positive-pressure ventilation (NPPV), has been developed for home ventilation of certain patients with chronic ventilatory insufficiency. We hypothesized that NPPV could be used in selected patients in whom intubation and mechanical ventilation were clearly indicated, but not immediately possible, or even contraindicated. Six patients were treated with NPPV during an episode of acute respiratory failure and enrolled in a prospective study. We found that NPPV was successful in avoiding intubation, but only in the three patients suffering from a restrictive pulmonary disorder, whereas the procedure was unsuccessful in patients with obstructive disorders. Moreover, in every patient, acute NPPV was very time-consuming for the nursing staff: in patients with restrictive disorders, a nurse had to monitor a patient submitted to NPPV during 41 +/- 9 percent of the duration of ventilation and during 91 +/- 9 percent of the NPPV time in patients with obstructive disorders. We conclude that acute NPPV may be attempted in selected patients with acute respiratory failure, predominantly patients with restrictive respiratory disorders, but that this procedure is very time-consuming for nurses.
气管插管和机械通气是治疗急性呼吸衰竭患者的成熟技术;然而,在某些情况下,由于各种原因无法安全使用这些操作。最近描述的一种非侵入性技术——鼻正压通气(NPPV),已被开发用于某些慢性通气功能不全患者的家庭通气。我们假设NPPV可用于某些明确需要气管插管和机械通气但无法立即进行甚至禁忌的特定患者。6例急性呼吸衰竭发作期间接受NPPV治疗的患者被纳入一项前瞻性研究。我们发现NPPV成功避免了气管插管,但仅在3例患有限制性肺部疾病的患者中成功,而该操作在阻塞性疾病患者中未成功。此外,对每位患者而言,急性NPPV对护理人员来说都非常耗时:在限制性疾病患者中,护士必须在通气时间的41±9%期间监测接受NPPV的患者,而在阻塞性疾病患者中则需在NPPV时间的91±9%期间进行监测。我们得出结论,对于某些急性呼吸衰竭患者,主要是患有限制性呼吸疾病的患者,可尝试进行急性NPPV,但该操作对护士来说非常耗时。