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雪松刨花对C3H-Avy fB小鼠垫料可能产生的致癌作用。

Possible carcinogenic effects of cedar shavings in bedding of C3H-Avy fB mice.

作者信息

Vlahakis G

出版信息

J Natl Cancer Inst. 1977 Jan;58(1):149-50. doi: 10.1093/jnci/58.1.149.

Abstract

C3H-AvyfB female mice were tested on bedding consisting only of low-resin pine and on bedding of pine plus cedar shavings. Tumor occurrences were similar in both groups of animals, with a slightly lower incidence and slightly higher average age for mammary gland tumors in the females on bedding of pine plus cedar. From these results, the high incidence of cancer in the C3H-AvyfB strain could not be attributed to the routine use of cedar shavings in the bedding material.

摘要

对C3H-AvyfB雌性小鼠在仅由低树脂松木制成的垫料上以及在松木加雪松刨花的垫料上进行了测试。两组动物的肿瘤发生率相似,在使用松木加雪松垫料的雌性小鼠中,乳腺肿瘤的发生率略低,平均年龄略高。从这些结果来看,C3H-AvyfB品系中癌症的高发生率不能归因于垫料材料中常规使用雪松刨花。

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