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多糖对红细胞与病毒反应的影响,尤其涉及腮腺炎病毒。

The effect of polysaccharides on the reaction between erythrocytes and viruses, with particular reference to mumps virus.

作者信息

GINSBERG H S, GOEBEL W F, HORSFALL F L

出版信息

J Exp Med. 1948 May 1;87(5):411-24. doi: 10.1084/jem.87.5.411.

Abstract

Polysaccharides which cause inhibition of the multiplication of mumps virus in the allantoic sac may or may not cause inhibition of hemagglutination by the virus. Moreover, such substances may or may not prevent adsorption of the virus by erythrocytes. The available evidence indicates that polysaccharides active as inhibitors do not block adsorption of mumps virus by cells of the living allantoic membrane. With influenza A, influenza B, and Newcastle disease viruses, as well as with PVM, there also appears to be a lack of correlation between the in vitro and in vivo inhibiting activity of polysaccharides.

摘要

能抑制腮腺炎病毒在尿囊囊中增殖的多糖,可能会也可能不会抑制该病毒的血凝反应。此外,这类物质可能会也可能不会阻止病毒被红细胞吸附。现有证据表明,具有抑制活性的多糖不会阻断腮腺炎病毒被活尿囊膜细胞吸附。对于甲型流感病毒、乙型流感病毒、新城疫病毒以及副粘病毒,多糖的体外和体内抑制活性之间似乎也缺乏相关性。

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