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多糖对红细胞与病毒反应的影响，尤其涉及腮腺炎病毒。

The effect of polysaccharides on the reaction between erythrocytes and viruses, with particular reference to mumps virus.

作者信息

GINSBERG H S, GOEBEL W F, HORSFALL F L

出版信息

J Exp Med. 1948 May 1;87(5):411-24. doi: 10.1084/jem.87.5.411.

DOI:10.1084/jem.87.5.411
PMID:18912892
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2135786/
Abstract

Polysaccharides which cause inhibition of the multiplication of mumps virus in the allantoic sac may or may not cause inhibition of hemagglutination by the virus. Moreover, such substances may or may not prevent adsorption of the virus by erythrocytes. The available evidence indicates that polysaccharides active as inhibitors do not block adsorption of mumps virus by cells of the living allantoic membrane. With influenza A, influenza B, and Newcastle disease viruses, as well as with PVM, there also appears to be a lack of correlation between the in vitro and in vivo inhibiting activity of polysaccharides.

摘要

能抑制腮腺炎病毒在尿囊囊中增殖的多糖，可能会也可能不会抑制该病毒的血凝反应。此外，这类物质可能会也可能不会阻止病毒被红细胞吸附。现有证据表明，具有抑制活性的多糖不会阻断腮腺炎病毒被活尿囊膜细胞吸附。对于甲型流感病毒、乙型流感病毒、新城疫病毒以及副粘病毒，多糖的体外和体内抑制活性之间似乎也缺乏相关性。

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1
The effect of polysaccharides on the reaction between erythrocytes and viruses, with particular reference to mumps virus.多糖对红细胞与病毒反应的影响，尤其涉及腮腺炎病毒。
J Exp Med. 1948 May 1;87(5):411-24. doi: 10.1084/jem.87.5.411.
2
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引用本文的文献

1
The inhibitory effect of polysaccharide on mumps virus multiplication.多糖对腮腺炎病毒增殖的抑制作用。
J Exp Med. 1948 May 1;87(5):385-410. doi: 10.1084/jem.87.5.385.
2
A resistant variant of mumps virus; multiplication of the variant in the presence of inhibitory quantities of Friedländer bacillus polysaccharide.一种腮腺炎病毒的抗性变体；该变体在存在抑制量的弗氏杆菌多糖的情况下增殖。
J Exp Med. 1949 Nov;90(5):393-407. doi: 10.1084/jem.90.5.393.
3
Concurrent infection with influenza virus and mumps virus or pneumonia virus of mice as bearing on the inhibition of virus multiplication by bacterial polysaccharides.流感病毒与小鼠腮腺炎病毒或肺炎病毒的并发感染与细菌多糖对病毒增殖的抑制作用的关系。
J Exp Med. 1949 Jan;89(1):37-52. doi: 10.1084/jem.89.1.37.
4
Mechanism of production of pulmonary lesions in mice by Newcastle disease virus (NDV).新城疫病毒（NDV）致小鼠肺部病变的机制
J Exp Med. 1951 Sep;94(3):191-211. doi: 10.1084/jem.94.3.191.
5
Therapy of infection with pneumonia virus of mice (PVM); effect of a polysaccharide on the multiplication cycles of the virus and on the course of the viral pneumonia.小鼠肺炎病毒（PVM）感染的治疗；一种多糖对病毒增殖周期及病毒性肺炎病程的影响。
J Exp Med. 1951 Feb;93(2):161-71. doi: 10.1084/jem.93.2.161.
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Studies on bacteriophage. II. Inhibition of lysis of Escherichia coli B by the somatic antigen of Phase II Shigella sonnei.噬菌体研究。II. 宋内志贺氏菌II相菌体抗原对大肠杆菌B型裂解的抑制作用
J Exp Med. 1950 Dec;92(6):527-43. doi: 10.1084/jem.92.6.527.
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Suppression of blood group agglutinability of human erythrocytes by certain bacterial polysaccharides.某些细菌多糖对人红细胞血型凝集性的抑制作用。
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Bull World Health Organ. 1961;24(1):115-9.
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[Protective effect of polysaccharide-like fractions of bacterial origin in an experimental virus infection].[细菌来源的多糖样组分在实验性病毒感染中的保护作用]
Experientia. 1956 Jun 15;12(6):213-4. doi: 10.1007/BF02170518.
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Inhibition of Theiler's encephalomyelitis virus (GDVII strain) of mice by an intestinal mucopolysaccharide. I. Biological properties and mechanism of action.一种肠道粘多糖对小鼠泰勒氏脑脊髓炎病毒（GDVII株）的抑制作用。I.生物学特性及作用机制
J Exp Med. 1953 Nov;98(5):399-415. doi: 10.1084/jem.98.5.399.

本文引用的文献

1
STUDIES ON A LUNG TISSUE COMPONENT WHICH COMBINES WITH PNEUMONIA VIRUS OF MICE (PVM).肺炎小鼠病毒（PVM）结合肺组织成分的研究
J Exp Med. 1947 Oct 31;86(5):393-407. doi: 10.1084/jem.86.5.393.
2
INHIBITION BY CERTAIN POLYSACCHARIDES OF HEMAGGLUTINATION AND OF MULTIPLICATION OF INFLUENZA VIRUS.某些多糖对血凝作用和流感病毒增殖的抑制作用。
J Exp Med. 1947 Jun 30;86(1):55-64. doi: 10.1084/jem.86.1.55.
3
THE MODIFYING EFFECTS OF CERTAIN SUBSTANCES OF BACTERIAL ORIGIN ON THE COURSE OF INFECTION WITH PNEUMONIA VIRUS OF MICE (PVM).某些细菌源物质对小鼠肺炎病毒（PVM）感染过程的影响。
J Exp Med. 1947 May 31;85(6):623-46. doi: 10.1084/jem.85.6.623.
4
STUDIES ON PNEUMONIA VIRUS OF MICE (PVM) : I. THE PRECISION OF MEASUREMENTS IN VIVO OF THE VIRUS AND ANTIBODIES AGAINST IT.关于鼠肺炎病毒（PVM）的研究：I. 病毒及其抗体在体内测量的精确性。
J Exp Med. 1946 Jan 1;83(1):25-42.
5
THE SOLUBLE SPECIFIC SUBSTANCE OF FRIEDLANDER'S BACILLUS : III. ON THE ISOLATION AND PROPERTIES OF THE SPECIFIC CARBOHYDRATES FROM TYPES A AND C FRIEDLANDER BACILLUS.弗赖登伯格杆菌可溶性特异性物质：III. 从 A 型和 C 型弗赖登伯格杆菌中分离特异性碳水化合物及其特性。
J Exp Med. 1927 Sep 30;46(4):601-7. doi: 10.1084/jem.46.4.601.
6
THE SOLUBLE SPECIFIC SUBSTANCE OF A STRAIN OF FRIEDLANDER'S BACILLUS : PAPER I.弗赖登堡氏杆菌可溶性特异性物质：论文 I。
J Exp Med. 1925 Oct 31;42(5):701-7. doi: 10.1084/jem.42.5.701.
7
The inhibitory effect of polysaccharide on mumps virus multiplication.多糖对腮腺炎病毒增殖的抑制作用。
J Exp Med. 1948 May 1;87(5):385-410. doi: 10.1084/jem.87.5.385.