Sampanis Ch
Diabetes Center, 2nd Department of Internal Medicine, Aristotle University of Thessaloniki, Hippokration General Hospital, Thessaloniki, Greece.
Hippokratia. 2008 Jan;12(1):22-7.
Diabetes mellitus is recognized as a leading cause of chronic kidney disease and end-stage renal failure. Chronic renal failure is associated with insulin resistance and, in advanced renal failure, decreased insulin degradation. Both of these abnormalities are partially reversed with the institution of dialysis. Except for diet with protein restriction, patients with diabetes should be preferably treated with insulin. The management of the patients with hyperglycemia and chronic renal failure calls for close collaboration between the diabetologist and the nephrologists. This collaboration is very important so that the patient will not be confused and will not lose confidence to the doctors. Furthermore good glycemic control in these patients seems to reduce microvascular and macrovascular complications.
糖尿病被认为是慢性肾脏病和终末期肾衰竭的主要原因。慢性肾衰竭与胰岛素抵抗有关，在晚期肾衰竭中，胰岛素降解减少。透析治疗可部分逆转这两种异常情况。除了限制蛋白质饮食外，糖尿病患者最好使用胰岛素治疗。糖尿病合并慢性肾衰竭患者的管理需要糖尿病专家和肾病专家密切合作。这种合作非常重要，这样患者就不会感到困惑，也不会对医生失去信心。此外，对这些患者进行良好的血糖控制似乎可以减少微血管和大血管并发症。
