Iaina Adrian, Silverberg Donald S, Wexler Dov, Iaina Nomy Levin
Department of Nephrology, Tel Aviv Medical Center, Israel.
Med Pregl. 2007;60 Suppl 2:145-50.
Congestive heart failure, chronic kidney insufficiency and anemia are often present in the same patient. We have coined this triad the cardio-renal anemia syndrome. We suggest that congestive heart failure can often cause chronic renal failure, with both diseases producing anemia. The anemia exacerbates the chronic heart failure, which then worsens the chronic renal failure, causing further anemia, in a vicious cycle. Together with early detection and treatment of the chronic heart failure, correction of the associated anemia with a combination of subcutaneous erythropoietin and intravenous iron will often alleviate the chronic heart failure and slow down or stop the progression of the associated chronic kidney insufficiency.
充血性心力衰竭、慢性肾功能不全和贫血常同时出现在同一患者身上。我们将这种三联征称为心肾贫血综合征。我们认为充血性心力衰竭常可导致慢性肾衰竭，这两种疾病都会引起贫血。贫血会加重慢性心力衰竭，进而使慢性肾衰竭恶化，导致进一步贫血，形成恶性循环。除了早期检测和治疗慢性心力衰竭外，联合皮下注射促红细胞生成素和静脉补铁纠正相关贫血，通常会缓解慢性心力衰竭，并减缓或阻止相关慢性肾功能不全的进展。
