Design of polymeric carriers for cancer-specific gene targeting: utilization of abnormal protein kinase Calpha activation in cancer cells.
作者信息
Kang Jeong-Hun, Asai Daisuke, Kim Jong-Hwan, Mori Takeshi, Toita Riki, Tomiyama Tetsuro, Asami Yoji, Oishi Jun, Sato Yuko T, Niidome Takuro, Jun Byungdug, Nakashima Hideki, Katayama Yoshiki
机构信息
Department of Applied Chemistry, Faculty of Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka, 819-0395, Japan.
出版信息
J Am Chem Soc. 2008 Nov 12;130(45):14906-7. doi: 10.1021/ja805364s. Epub 2008 Oct 18.
PMID:18928283
Abstract
We succeeded in cancer cell specific gene expression by using a polyplex responsive to protein kinase Calpha, which is activated in various types of cancer cells.
摘要
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