Borrego Galán J C, de Portugal Alvarez J, Sánchez Rodríguez A, Chimpen Ruiz V, Martín Oterino J A, Gutiérrez San Pedro N
Departamento de Medicina Interna, Hospital Clínico Universitario de Salamanca.
An Med Interna. 1991 Mar;8(3):111-5.
Fibronectin (Fn) is a glycoprotein secreted principally by vascular endothelial cells and its main function is to maintain the adhesion between the various cells and the substrates. Owing to these two features, the glycoprotein participates in several pathologies affecting blood vessels, such as atherosclerosis and diabetes mellitus (DM). In this paper, we studied the quantitative differences of this protein in diabetic patients with associated macro and microangiopathy.
纤连蛋白（Fn）是一种主要由血管内皮细胞分泌的糖蛋白，其主要功能是维持各种细胞与底物之间的黏附。由于这两个特性，这种糖蛋白参与了多种影响血管的病理过程，如动脉粥样硬化和糖尿病（DM）。在本文中，我们研究了伴有大血管和微血管病变的糖尿病患者中这种蛋白质的定量差异。
