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马尔代夫基孔肯雅热的首次报告。

First report of chikungunya from the Maldives.

作者信息

Yoosuf Abdul Azeez, Shiham Ibrahim, Mohamed Ahmed Jamsheed, Ali Geela, Luna J M, Pandav R, Gongal G N, Nisaluk Ananda, Jarman Richard G, Gibbons Robert V

机构信息

Ministry of Health, Malé 20379, Republic of Maldives.

出版信息

Trans R Soc Trop Med Hyg. 2009 Feb;103(2):192-6. doi: 10.1016/j.trstmh.2008.09.006. Epub 2008 Oct 17.

DOI:10.1016/j.trstmh.2008.09.006
PMID:18930301
Abstract

An outbreak, characterised by fever, arthralgia and myalgia, in Malé and other islands of the Maldives began in December 2006. The illness was suspected as being due to chikungunya virus based on clinical symptoms and the prevailing chikungunya epidemic in the Indian Ocean region. The Department of Public Health initiated an investigation and collected blood samples from 67 patients; 21% were IgM-positive for chikungunya and 96% were PCR-positive. Six percent were positive for dengue by enzyme immunosorbent assay and 4% had evidence of dual infection. This is the first time that chikungunya fever has been confirmed in the Maldives. A total of 11,879 suspected and confirmed cases affecting 61% of inhabited islands (attack rate ranging from 0% to 72% on individual islands) were reported by the end of the epidemic in April 2007.

摘要

2006年12月,马尔代夫首都马累及其他岛屿开始出现以发热、关节痛和肌痛为特征的疫情。根据临床症状以及印度洋地区当时流行的基孔肯雅热疫情,怀疑该病由基孔肯雅病毒引起。公共卫生部展开调查,从67名患者身上采集了血样;21%的患者基孔肯雅病毒IgM呈阳性,96%的患者PCR呈阳性。6%的患者通过酶联免疫吸附测定法检测出登革热呈阳性,4%的患者有双重感染的迹象。这是马尔代夫首次确诊基孔肯雅热。截至2007年4月疫情结束时,共报告了11879例疑似和确诊病例,影响了61%有人居住的岛屿(各岛屿的发病率从0%到72%不等)。

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