Drolet Beth A, Swanson Elizabeth A, Frieden Ilona J
Department of Dermatology and Pediatrics, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
J Pediatr. 2008 Nov;153(5):712-5, 715.e1. doi: 10.1016/j.jpeds.2008.05.043.
A total of 420 children with infantile hemangioma (IH) were compared with 353 age-matched controls. Using multivariate logistic regression, low birth weight was the most significant risk factor; for every 500-g decrease in birth weight, the risk of IH increased by 40%. A positive family history also increased the risk of IH (33% vs 15% of controls; P < .001).
共有420例患有婴儿血管瘤（IH）的儿童与353例年龄匹配的对照组儿童进行了比较。通过多因素逻辑回归分析，低出生体重是最显著的风险因素；出生体重每降低500克，患IH的风险增加40%。阳性家族史也会增加患IH的风险（对照组为15%，有家族史者为33%；P <.001）。
