Sayers Eric W, Barrett Tanya, Benson Dennis A, Bryant Stephen H, Canese Kathi, Chetvernin Vyacheslav, Church Deanna M, DiCuccio Michael, Edgar Ron, Federhen Scott, Feolo Michael, Geer Lewis Y, Helmberg Wolfgang, Kapustin Yuri, Landsman David, Lipman David J, Madden Thomas L, Maglott Donna R, Miller Vadim, Mizrachi Ilene, Ostell James, Pruitt Kim D, Schuler Gregory D, Sequeira Edwin, Sherry Stephen T, Shumway Martin, Sirotkin Karl, Souvorov Alexandre, Starchenko Grigory, Tatusova Tatiana A, Wagner Lukas, Yaschenko Eugene, Ye Jian
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Building 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA.
Nucleic Acids Res. 2009 Jan;37(Database issue):D5-15. doi: 10.1093/nar/gkn741. Epub 2008 Oct 21.
In addition to maintaining the GenBank nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the data in GenBank and other biological data made available through the NCBI web site. NCBI resources include Entrez, the Entrez Programming Utilities, MyNCBI, PubMed, PubMed Central, Entrez Gene, the NCBI Taxonomy Browser, BLAST, BLAST Link (BLink), Electronic PCR, OrfFinder, Spidey, Splign, RefSeq, UniGene, HomoloGene, ProtEST, dbMHC, dbSNP, Cancer Chromosomes, Entrez Genomes and related tools, the Map Viewer, Model Maker, Evidence Viewer, Clusters of Orthologous Groups (COGs), Retroviral Genotyping Tools, HIV-1/Human Protein Interaction Database, Gene Expression Omnibus (GEO), Entrez Probe, GENSAT, Online Mendelian Inheritance in Man (OMIM), Online Mendelian Inheritance in Animals (OMIA), the Molecular Modeling Database (MMDB), the Conserved Domain Database (CDD), the Conserved Domain Architecture Retrieval Tool (CDART) and the PubChem suite of small molecule databases. Augmenting many of the web applications is custom implementation of the BLAST program optimized to search specialized data sets. All of the resources can be accessed through the NCBI home page at www.ncbi.nlm.nih.gov.
除维护GenBank核酸序列数据库外,美国国立医学图书馆国家生物技术信息中心(NCBI)还为GenBank中的数据以及通过NCBI网站提供的其他生物学数据提供分析和检索资源。NCBI的资源包括Entrez、Entrez编程实用程序、MyNCBI、PubMed、PubMed Central、Entrez Gene、NCBI分类浏览器、BLAST、BLAST链接(BLink)、电子PCR、OrfFinder、Spidey、Splign、RefSeq、UniGene、HomoloGene、ProtEST、dbMHC、dbSNP、癌症染色体、Entrez基因组及相关工具、地图查看器、模型制作器、证据查看器、直系同源簇(COG)、逆转录病毒基因分型工具、HIV-1/人类蛋白质相互作用数据库、基因表达综合数据库(GEO)、Entrez探针、基因表达神经系统图谱(GENSAT)、《人类孟德尔遗传在线》(OMIM)、《动物孟德尔遗传在线》(OMIA)、分子模型数据库(MMDB)、保守结构域数据库(CDD)、保守结构域架构检索工具(CDART)以及小分子数据库的PubChem套件。许多网络应用程序都增强了经过优化以搜索特定数据集的BLAST程序的定制实现。所有资源均可通过NCBI主页www.ncbi.nlm.nih.gov进行访问。