Mythilypriya Rajendran, Shanthi Palanivelu, Sachdanandam Panchanadam
Department of Medical Biochemistry, Dr. ALM. Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani Campus, Chennai 600 113, India.
Inflammation. 2008 Dec;31(6):391-8. doi: 10.1007/s10753-008-9090-2.
The present study was designed to evaluate the antiinflammatory properties of Kalpaamruthaa (KA) a modified indigenous Siddha formulation constituting Semecarpus anacardium nut milk extract (SA), Emblica officinalis (EO) and honey in acute and chronic antiinflammatory studies. A dose of 150 mg/kg b.wt. of SA and KA were used for the present studies. The effect of KA was compared with standard drug diclofenac sodium. It was observed that the drug KA exhibited enhanced effect on antiinflammatory and antiarthritic properties than sole SA treatment and the collective effect of KA might be due to the combined interactions of the phytochemicals such as flavonoids, tannins and other compounds such as vitamin c present in KA.
本研究旨在评估Kalpaamruthaa(KA)的抗炎特性,KA是一种改良的印度传统悉达配方,由印度楝树坚果奶提取物(SA)、余甘子(EO)和蜂蜜组成,用于急性和慢性抗炎研究。本研究使用了150mg/kg体重的SA和KA剂量。将KA的效果与标准药物双氯芬酸钠进行比较。观察到,与单独使用SA治疗相比,药物KA在抗炎和抗关节炎特性方面表现出更强的效果,KA的综合作用可能归因于KA中存在的黄酮类、单宁等植物化学物质与维生素C等其他化合物的联合相互作用。