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囊性肾瘤:一例病例报告及文献综述

Cystic nephroma: a case report and review of the literature.

作者信息

Stamatiou Konstantinos, Polizois Konstantinos, Kollaitis Gerasimos, Dahanis Stefanos, Zafeiropoulos Grigoris, Leventis Christos, Lambou Theocharis

机构信息

Department of Urology, Thriasio Hospital, Elefsina, Greece.

出版信息

Cases J. 2008 Oct 23;1(1):267. doi: 10.1186/1757-1626-1-267.

Abstract

BACKGROUND

The spectrum of cystic renal neoplasms includes both benign and malignant tumors and the order is as follows: benign multilocular cyst, multilocular cystic renal cell cancer and cystic renal cell cancer. Gross similarities among multicystic tumors of the kidney may cause conflict in the diagnosis and treatment of these lesions.

RESULTS

We report a 53-year old male patient who presented with a mild persistent left flank pain and a painful left renal mass. After a series of examinations including abdominal ultrasound, intravenous pyelography and computed tomography, he underwent radical nephrectomy. Microscopic examination of the resected tissue showed the typical characteristics of a cystic nephroma. Immuno-histological staining of the epithelium of the tumour with CK 19 suggested an aberrant renal tubular differentiation.

CONCLUSION

Cystic nephroma is a relatively rare benign lesion of the kidney. Since 1892, only 200 cases have been reported in the international literature. The non-specific clinical findings and the poor contribution of imaging examinations make the preoperative distinction from other cystic renal neoplasias difficult. Final diagnosis can be established in the histopathological examination of the completely rejected tumor in the pathology laboratory.

摘要

背景

肾囊性肿瘤谱包括良性和恶性肿瘤,顺序如下:良性多房囊肿、多房囊性肾细胞癌和囊性肾细胞癌。肾多囊性肿瘤之间的大体相似性可能导致这些病变的诊断和治疗存在冲突。

结果

我们报告一名53岁男性患者,表现为轻度持续性左腰痛和左侧疼痛性肾肿块。经过包括腹部超声、静脉肾盂造影和计算机断层扫描在内的一系列检查后,他接受了根治性肾切除术。对切除组织的显微镜检查显示出囊性肾瘤的典型特征。用CK 19对肿瘤上皮进行免疫组织化学染色提示肾小管分化异常。

结论

囊性肾瘤是一种相对罕见的肾脏良性病变。自1892年以来,国际文献中仅报道了200例。非特异性临床表现以及影像学检查作用有限使得术前难以与其他肾囊性肿瘤相鉴别。最终诊断可在病理实验室对完整切除肿瘤进行组织病理学检查后确立。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f377/2582226/d39bdf9b2416/1757-1626-1-267-1.jpg

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