Boyce Stephen, Harrison David
Department of Surgery, University of Edinburgh, Royal Infirmary of Edinburgh, Scotland.
Lab Anim (NY). 2008 Nov;37(11):529-32. doi: 10.1038/laban1108-529.
The technique of partial hepatectomy is widely used to model liver regeneration and cell cycle dynamics in vivo. Because murine gene expression can be manipulated relatively easily, partial hepatectomy in mice is a useful tool for exploring the contributions of different genes to such hepatic processes. The authors present a straightforward method of partial hepatectomy in the mouse.
部分肝切除术技术被广泛用于在体内模拟肝再生和细胞周期动态。由于小鼠基因表达相对容易操控，小鼠部分肝切除术是探索不同基因对这类肝脏过程贡献的有用工具。作者介绍了一种在小鼠中进行部分肝切除术的简单方法。
