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通过连续波多普勒计算人体左心室舒张时间常数-Tau

Calculation of left ventricular relaxation time constant-Tau in humans by continuous-wave Doppler.

作者信息

Bai Xufang

机构信息

Henderson Research Center, McMaster University, Hamilton, Ontario, Canada.

出版信息

Open Cardiovasc Med J. 2008;2:9-11. doi: 10.2174/1874192400802010009. Epub 2008 Apr 25.

DOI:10.2174/1874192400802010009
PMID:18949092
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2570574/
Abstract

Left ventricular relaxation time constant, Tau, is the best index to evaluate left ventricular diastolic function, but the measurement is only available traditionally in catheter lab. In Echo lab, several methods of non-invasive measurement of Tau have been tried since 1992, however almost all the methods are still utilizing the same formula to calculate Tau as in catheter lab, which makes them inconvenient, time-consuming and sometimes not very accurate. Based on Weiss' formula and simplified Bernoulli's equation, a simple method is developed by pure mathematical derivative to calculate Tau by continuous-wave Doppler in patients with mitral regurgitation.

摘要

左心室舒张时间常数Tau是评估左心室舒张功能的最佳指标，但传统上只有在导管实验室才能进行测量。自1992年以来，在超声心动图实验室尝试了几种无创测量Tau的方法，然而几乎所有方法仍使用与导管实验室相同的公式来计算Tau，这使得它们不方便、耗时，有时还不太准确。基于魏斯公式和简化的伯努利方程，通过纯数学推导开发了一种简单方法，用于通过连续波多普勒对二尖瓣反流患者计算Tau。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2444/2570574/a313ba1e88df/TOCMJ-2-9_F3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2444/2570574/0677531a33f8/TOCMJ-2-9_F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2444/2570574/2151231c70a8/TOCMJ-2-9_F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2444/2570574/a313ba1e88df/TOCMJ-2-9_F3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2444/2570574/0677531a33f8/TOCMJ-2-9_F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2444/2570574/2151231c70a8/TOCMJ-2-9_F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2444/2570574/a313ba1e88df/TOCMJ-2-9_F3.jpg

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本文引用的文献

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Noninvasive assessment of the ventricular relaxation time constant (tau) in humans by Doppler echocardiography.通过多普勒超声心动图对人体心室舒张时间常数（tau）进行无创评估。
Circulation. 1997 Jan 7;95(1):151-5. doi: 10.1161/01.cir.95.1.151.
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Noninvasive measurement of rate of left ventricular relaxation by Doppler echocardiography. Validation with simultaneous cardiac catheterization.
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Continuous wave Doppler echocardiography for noninvasive assessment of left ventricular dP/dt and relaxation time constant from mitral regurgitant spectra in patients.连续波多普勒超声心动图用于无创评估患者二尖瓣反流频谱中的左心室dp/dt和舒张时间常数。
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