Bai Xufang
Henderson Research Center, McMaster University, Hamilton, Ontario, L8V 1C3, Canada.
Open Cardiovasc Med J. 2008;2:28-30. doi: 10.2174/1874192400802010028. Epub 2008 Apr 25.
Left ventricular relaxation time constant, Tau, is the best index to evaluate left ventricular diastolic function. The measurement is only available traditionally in catheter lab. In Echo lab, several methods of non-invasive measurement of Tau have been tried since 1992, however almost all the methods are still utilizing the same formula to calculate Tau as in catheter lab, which makes them inconvenient, time-consuming and sometimes not very accurate. A simple method to calculate Tau in patients with mitral regurgitation has been developed just based on Weiss' formula and simplified Bernoulli's equation. Similarly, formulas are developed here by pure mathematical derivative to calculate Tau by continuous-wave Doppler in patients with aortic regurgitation.
左心室舒张时间常数Tau是评估左心室舒张功能的最佳指标。传统上,该测量仅能在导管室进行。自1992年以来,在超声心动图实验室中尝试了几种无创测量Tau的方法,然而几乎所有方法仍使用与导管室相同的公式来计算Tau,这使得它们不方便、耗时,有时还不太准确。基于魏斯公式和简化的伯努利方程,开发了一种简单的方法来计算二尖瓣反流患者的Tau。同样,本文通过纯数学推导得出公式,以通过连续波多普勒计算主动脉瓣反流患者的Tau。