脑卒中伴空间忽视患者顶叶皮质直流电脑极化后视觉扫描功能的改善
Improvement of visual scanning after DC brain polarization of parietal cortex in stroke patients with spatial neglect.
作者信息
Ko Myoung-Hwan, Han Sang-Hyoung, Park Sung-Hee, Seo Jeong-Hwan, Kim Yun-Hee
机构信息
Department of Physical Medicine and Rehabilitation, Institute for Medical Sciences & Research Institute of Clinical Medicine, Chonbuk National University Medical School, 634-18 Keumam-dong, Dukjin-ku, Jeonju, Jeonbuk 561-712, Republic of Korea.
出版信息
Neurosci Lett. 2008 Dec 26;448(2):171-4. doi: 10.1016/j.neulet.2008.10.050. Epub 2008 Oct 21.
Previous studies have demonstrated that transcranial direct current (DC) brain polarization can modulate cortical excitability in the human brain. We investigated the effect of anodal DC brain polarization of right parietal cortex on visuospatial scanning in subacute stroke patients with spatial neglect. The patients underwent two neglect tests - figure cancellation and line bisection - before and immediately after anodal DC or sham in a double-blind protocol. Anodal DC was applied to the scalp over the right posterior parietal cortex (PPC) with an intensity of 2.0 mA for 20 min. Anodal DC brain polarization, but not sham, led to significant improvement in the both neglect tests. These results document a beneficial effect of DC brain polarization on neglect.
先前的研究表明，经颅直流电（DC）脑极化可调节人脑的皮质兴奋性。我们研究了右顶叶皮质阳极直流电脑极化对存在空间忽视的亚急性中风患者视觉空间扫描的影响。患者在双盲方案下，于阳极直流电或假刺激之前及之后立即接受两项忽视测试——图形删失和线段二等分。将强度为2.0 mA的阳极直流电施加于右后顶叶皮质（PPC）上方的头皮，持续20分钟。阳极直流电脑极化而非假刺激，使两项忽视测试均有显著改善。这些结果证明了直流电脑极化对忽视具有有益作用。
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