Department of Chemistry, Washington State University, Pullman, WA 99164-4630, USA.
Talanta. 2001 Mar 30;54(1):171-9. doi: 10.1016/s0039-9140(00)00663-9.
The use of ion mobility spectrometry systems to detect explosives in high security situations creates a need to determine compounds that interfere and may compromise accurate detection. This is the first study to identify possible interfering air contaminants common in airport settings by IMS. Seventeen suspected contaminants from four major sources were investigated. Due to the ionization selectivity gained by employing chloride reactant ion chemistry, only 7 of the 17 compounds showed an IMS response. Of those seven compounds, only 4,6-dinitro-o-cresol (4,6DNOC) was found to have a similar mobility to 2,4,6-trinitrotoluene (TNT) with K(o) values of 1.55 and 1.50 cm(2) V(-1) s(-1), respectively. Although baseline resolution between TNT and 4,6DNOC was not achieved, the drift time for TNT was still easily identified. Alkyl-nitrated phenols, due to acidic fog, responded the strongest in the IMS. The effect of contamination on TNT sensitivity was investigated. Charge competition between TNT and 2,4-dinitrophenol (2,4DNP) was found to occur and to effect TNT sensitivity.
利用离子迁移谱系统在高安全环境下检测爆炸物，这就需要确定可能会干扰并影响准确检测的化合物。这是首次通过 IMS 确定机场环境中常见的可能干扰空气污染物的研究。研究人员调查了来自四个主要来源的 17 种可疑污染物。由于采用氯化物反应离子化学获得了离子化选择性，只有 17 种化合物中的 7 种显示出 IMS 响应。在这七种化合物中，只有 4,6-二硝基邻甲酚（4,6DNOC）与 2,4,6-三硝基甲苯（TNT）具有相似的迁移率，K(o) 值分别为 1.55 和 1.50 cm(2) V(-1) s(-1)。尽管未实现 TNT 和 4,6DNOC 之间的基线分离，但仍可轻松识别 TNT 的漂移时间。由于酸性雾，烷基硝酚的响应在 IMS 中最强。还研究了污染对 TNT 灵敏度的影响。发现 TNT 和 2,4-二硝基苯酚（2,4DNP）之间存在电荷竞争，这会影响 TNT 的灵敏度。
