Schaberg T, Lode H
Pneumologie I (Infektiologie und Immunologie), Krankenhaus Zehlendorf-Heckeshorn, Berlin.
Z Gesamte Inn Med. 1991 Jun;46(8):276-9.
The here described investigations show correspondingly that the administration of isoniazid, rifampicin and pyrazinamide in a fixed combination of the administration of the individual substances is bioequivalent under pharmacokinetic aspects. Further investigations on large populations of patients must, however, still confirm whether or not the advantages of the fix combination striven for or theoretically to be expected can be proved in practice.
此处所述的研究相应地表明，异烟肼、利福平及吡嗪酰胺按固定组合给药，与单独给药相比，在药代动力学方面具有生物等效性。然而，仍需对大量患者群体进行进一步研究，以证实所追求的或理论上预期的固定组合的优势在实际应用中是否能够得到验证。
