Mullol J, Valero A, Alobid I, Bartra J, Navarro A M, Chivato T, Khaltaev N, Bousquet J
Rhinology Unit et Smell Clinic, ENT Department, Hospital Clinic - IDIBAPS, Barcelona, Catalonia, Spain.
J Investig Allergol Clin Immunol. 2008;18(5):327-34.
Allergic rhinitis is a global health problem. Over 600 million patients suffer from this disease worldwide. ARIA (Allergic Rhinitis and its Impact on Asthma), an evidence-based document, was produced and published in 2001 using an extensive review of the available literature. The ARIA 2008 update was recently published and covers tertiary prevention of allergy, pharmacologic treatments, and immunotherapy. Nonallergic rhinitis is still a controversial area and may pose some treatment problems. Another important aspect of the ARIA update is the comorbidity of allergic rhinitis, in particular, asthma. The recommendations of the 2008 ARIA Update, as in 2001, are that patients with allergic rhinitis, particularly if persistent, should be evaluated for asthma, patients with asthma should be evaluated for rhinitis, and an effective and safe combination strategy should be used to treat diseases of the upper and lower airways. Over the last few years, severa studies performed in Spain report new data on the prevalence of allergic rhinitis sensitivity to common aeroallergens, comorbidity of allergic rhinitis and asthma, and impact on quality of life. The studies reviewed in this manuscript confirm--as do those from other developed countries--the enormous impact of the disease on society and health care in Spain.
变应性鼻炎是一个全球性的健康问题。全球有超过6亿患者受此疾病困扰。变应性鼻炎及其对哮喘的影响（ARIA）是一份基于证据的文件，于2001年通过广泛回顾现有文献编制并发表。ARIA 2008年更新版最近已发布，内容涵盖变应性疾病的三级预防、药物治疗和免疫疗法。非变应性鼻炎仍是一个存在争议的领域，可能会带来一些治疗难题。ARIA更新版的另一个重要方面是变应性鼻炎的合并症，尤其是哮喘。与2001年一样，2008年ARIA更新版的建议是，变应性鼻炎患者，尤其是持续性患者，应接受哮喘评估；哮喘患者应接受鼻炎评估；应采用有效且安全的联合策略来治疗上、下气道疾病。在过去几年中，西班牙进行的多项研究报告了有关变应性鼻炎对常见气传变应原的敏感性患病率、变应性鼻炎与哮喘的合并症以及对生活质量影响的新数据。本手稿中综述的研究证实——其他发达国家的研究也证实——该疾病对西班牙社会和医疗保健产生了巨大影响。
