Second Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou, China.
Department of general practice, Anhui Medical University, He Fei, China.
Medicine (Baltimore). 2023 Mar 3;102(9):e32997. doi: 10.1097/MD.0000000000032997.
At present, there are many commonly used moxibustion methods in clinical practice, but it is unclear which moxibustion is more suitable for the treatment of allergic rhinitis (AR), so we used a network meta-analysis to analyze the effectiveness of various moxibustion types in the treatment of AR.
We searched 8 databases for comprehensive inclusion of randomized controlled trials (RCTs) for moxibustion in the treatment of allergic rhinitis. The search time was from the beginning of database establishment to January 2022. The Cochrane Risk of Bias tool was used to analyze the risk of bias of the included RCTs. Bayesian network meta-analysis of the included RCT was performed using the R software GEMTC and the RJAGS package.
A total of 38 RCTs were included, involving 4257 patients and 9 types of moxibustion. The network meta-analysis results revealed that heat-sensitive moxibustion (HSM) not only has the best effect in terms of effective rate (Odd ratio [OR]: 32.77, 95% Credible intervals [CrIs]: 1.86-1360.2) among the nine types of moxibustion, but also has good effect in improving the quality of life score (standard mean differences [SMD]: 0.6, 95% CrIs: 0.07-1.29). In terms of improving IgE and VAS scores, various types of moxibustion were comparable to the efficacy of western medicine.
The results showed that HSM was the most effective treatment for AR compared with other types of moxibustion. Therefore, it can be regarded as a complementary and alternative therapy for AR patients with poor effects of traditional treatment and patients who are susceptible to adverse reactions of western medicine.
目前，临床实践中有许多常用的艾灸方法，但哪种艾灸更适合治疗过敏性鼻炎（AR）尚不清楚，因此我们采用网络荟萃分析来分析各种艾灸类型治疗 AR 的效果。
我们全面检索了 8 个数据库中艾灸治疗过敏性鼻炎的随机对照试验（RCT）。检索时间从数据库建立之初到 2022 年 1 月。采用 Cochrane 偏倚风险工具对纳入的 RCT 进行偏倚风险分析。使用 R 软件 GEMTC 和 RJAGS 包对纳入的 RCT 进行贝叶斯网络荟萃分析。
共纳入 38 项 RCT，涉及 4257 例患者和 9 种艾灸方法。网络荟萃分析结果显示，热敏灸（HSM）不仅在 9 种艾灸方法中的有效率方面效果最好（优势比[OR]：32.77，95%可信区间[CrI]：1.86-1360.2），而且在提高生活质量评分方面也有较好的效果（标准均数差[SMD]：0.6，95% CrI：0.07-1.29）。在改善 IgE 和 VAS 评分方面，各种艾灸方法与西药的疗效相当。
结果表明，与其他艾灸方法相比，HSM 是治疗 AR 最有效的方法。因此，它可以作为传统治疗效果不佳的 AR 患者和对西药不良反应敏感的患者的一种补充和替代治疗方法。
