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儿童过敏性鼻炎的新进展。

New progress in pediatric allergic rhinitis.

机构信息

Department of Ophthalmology and Otolaryngology, Jingmen Centra Hospital, Jingmen Central Hospital Affiliated to Jingchu University of Technology, Jingmen, Hubei, China.

Department of Infectious Disease, Jingmen Central Hospital, Jingmen Central Hospital Affiliated to Jingchu University of Technology, Jingmen, Hubei, China.

出版信息

Front Immunol. 2024 Sep 16;15:1452410. doi: 10.3389/fimmu.2024.1452410. eCollection 2024.

DOI:10.3389/fimmu.2024.1452410
PMID:39351215
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11439695/
Abstract

The prevalence of allergic rhinitis (AR) in children is steadily increasing, and its onset is closely associated with genetic factors, living environment, and exposure to allergens. In recent years, an increasing number of diagnostic methods have been employed to assist in diagnosing AR. In addition to pharmaceutical treatments, personalized approaches such as environmental control and allergen-specific immunotherapy are gradually gaining popularity. In this article, we reviewed recent research on the etiology, diagnostic classification, treatment methods, and health management of AR in children. These insights will benefit the implementation of personalized diagnosis and treatment for children with AR, promoting health management strategies that improve symptoms and quality of life.

摘要

儿童变应性鼻炎(AR)的患病率呈稳步上升趋势,其发病与遗传因素、生活环境和过敏原暴露密切相关。近年来,越来越多的诊断方法被用于辅助 AR 的诊断。除了药物治疗外,环境控制和过敏原特异性免疫治疗等个性化方法也逐渐受到关注。本文就儿童 AR 的病因、诊断分类、治疗方法和健康管理等方面的最新研究进展进行综述,以期为儿童 AR 的个体化诊治实施提供参考,制定改善症状和生活质量的健康管理策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2e0/11439695/189b042a3a63/fimmu-15-1452410-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2e0/11439695/5e7fba7c8e5c/fimmu-15-1452410-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2e0/11439695/189b042a3a63/fimmu-15-1452410-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2e0/11439695/5e7fba7c8e5c/fimmu-15-1452410-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2e0/11439695/189b042a3a63/fimmu-15-1452410-g002.jpg

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本文引用的文献

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Early-life gut microbiota associates with allergic rhinitis during 13-year follow-up in a Finnish probiotic intervention cohort.在一项芬兰益生菌干预队列的 13 年随访中,早期肠道微生物群与过敏性鼻炎有关。
Microbiol Spectr. 2024 Jun 4;12(6):e0413523. doi: 10.1128/spectrum.04135-23. Epub 2024 Apr 30.
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Genome-wide Association Study of Susceptibility Loci for Self-Reported Atopic Dermatitis and Allergic Rhinitis in the Korean Population.
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Full Breastfeeding and Allergic Diseases-Long-Term Protection or Rebound Effects?纯母乳喂养与过敏性疾病——长期保护还是反弹效应?
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The causality between intestinal flora and allergic diseases: Insights from a bi-directional two-sample Mendelian randomization analysis.肠道菌群与过敏性疾病的因果关系:来自双向两样本孟德尔随机化分析的见解。
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J Allergy Clin Immunol Pract. 2023 Mar;11(3):773-796. doi: 10.1016/j.jaip.2023.01.007.
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