Chan Raymond C K, Huang Jia, Di Xin
Neuropsychology and Applied Cognitive Neuroscience Laboratory, Institute of Psychology, Chinese Academy of Sciences, Beijing, China.
Brain Res Rev. 2009 Mar;59(2):316-23. doi: 10.1016/j.brainresrev.2008.09.003. Epub 2008 Oct 17.
The importance of the cerebellum in coordinates of movement has been established by lesion studies. However, there is no clear understanding of whether there is consistent activation in cerebellum across various motor task complexities or how different parts of the cerebellum contribute to finger coordinates in dexterous manipulation. This article reviews imaging studies with data from healthy subjects. A mini meta-analysis using label-based and activation likelihood estimation (ALE) methods reveals that ipsilateral anterior and vermis regions of the cerebellum were consistently activated across various dexterous movement complexities and were associated with finger and hand movement.
小脑在运动协调中的重要性已通过损伤研究得以确立。然而,对于在各种运动任务复杂性下小脑是否存在一致的激活,或者小脑的不同部分如何在灵巧操作中对手指协调发挥作用,目前尚无明确认识。本文回顾了针对健康受试者数据的成像研究。一项使用基于标签和激活可能性估计(ALE)方法的小型荟萃分析表明,小脑的同侧前部和蚓部区域在各种灵巧运动复杂性情况下均持续被激活,且与手指和手部运动相关。