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Neuroterrain 3D 鼠脑图谱

The Neuroterrain 3D Mouse Brain Atlas.

机构信息

Department of Neurobiology and Anatomy, Drexel University College of Medicine Philadelphia, PA, USA.

出版信息

Front Neuroinform. 2008 Jul 19;2:3. doi: 10.3389/neuro.11.003.2008. eCollection 2008.

Abstract

A significant objective of neuroinformatics is the construction of tools to readily access, search, and analyze anatomical imagery. This goal can be subdivided into development of the necessary databases and of the computer vision tools for image analysis. When considering mesoscale images, the latter tools can be further divided into registration algorithms and anatomical models. The models are atlases that contain both bitmap images and templates of anatomical boundaries. We report here on construction of such a model for the C57BL/6J mouse. The intended purpose of this atlas is to aid in automated delineation of the Mouse Brain Library, a database of brain histological images of importance to neurogenetic research.

摘要

神经信息学的一个重要目标是构建工具,以便于访问、搜索和分析解剖图像。这一目标可以细分为开发必要的数据库和用于图像分析的计算机视觉工具。在考虑中尺度图像时,后者的工具可以进一步分为注册算法和解剖模型。这些模型是包含位图图像和解剖边界模板的图谱。我们在此报告构建这样一个用于 C57BL/6J 小鼠的模型。该图谱的目的是帮助自动描绘 Mouse Brain Library,这是一个对神经遗传研究很重要的脑组织学图像数据库。

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