一种新的单萜生物碱及鸡蛋花的其他成分。

A new monoterpene alkaloid and other constituents of Plumeria acutifolia.

作者信息

Hassan Emad M, Shahat Abdelaaty A, Ibrahim Nabawya A, Vlietinck Arnold J, Apers Sandra, Pieters Luc

机构信息

Department of Medicinal and Aromatic Plants, National Research Centre, Dokki, Cairo, Egypt.

出版信息

Planta Med. 2008 Nov;74(14):1749-50. doi: 10.1055/s-0028-1088317. Epub 2008 Oct 30.

DOI:10.1055/s-0028-1088317

PMID:18975263

Abstract

Phytochemical investigation of the methanolic extract of Plumeria acutifolia (Apocynaceae) leaves has led to the isolation and identification by spectroscopic means of a new monoterpene alkaloid, (R)-4'-((S)-1-hydroxyethyl)-5,6-dihydro-5' H-spiro[cyclopenta[C]pyridine-7,2'-furan)-5'-one, for which the name plumerianine was adopted, the iridoid 15-demethylplumeride, and three known triterpenes, i. e., lupeol, uvaol and ursolic acid.

摘要

对鸡蛋花（夹竹桃科）叶片甲醇提取物进行的植物化学研究，通过光谱手段分离并鉴定出一种新的单萜生物碱，即（R）-4'-（（S）-1-羟乙基）-5,6-二氢-5'H-螺[环戊并[c]吡啶-7,2'-呋喃]-5'-酮，其被命名为鸡蛋花宁，还鉴定出环烯醚萜15-去甲基鸡蛋花苷，以及三种已知的三萜类化合物，即羽扇豆醇、乌索醇和熊果酸。