Severino S K, Wagner D R, Moline M L, Hurt S W, Pollak C P, Zendell S
Department of Psychiatry, New York Hospital-Cornell Medical Center-Westchester Division, White Plains 10605.
Am J Psychiatry. 1991 Oct;148(10):1329-35. doi: 10.1176/ajp.148.10.1329.
Because women with late luteal phase dysphoric disorder (LLPDD) experience symptomatic affective states predictably, they can be studied to determine whether there are biological findings related solely to the clinically symptomatic state. The authors sought to answer the question, Does body temperature change with affective state?
The core body temperature and motor activity patterns of 10 women with premenstrual syndrome (PMS), six of whom also met criteria for LLPDD, and no other psychological or medical illness were compared to those of six women with chronic, noncyclic dysphoria and six asymptomatic comparison women at four phases of the menstrual cycle.
The nocturnal temperatures of the women with PMS/LLPDD were significantly higher than those of the comparison subjects across the entire menstrual cycle, but there were no differences in nocturnal activity levels. The women with noncyclic dysphoria had a mean nocturnal temperature in the follicular phase as high as that of the women with PMS/LLPDD. The temperatures of all women were higher in the luteal phase than in the follicular phase.
These findings suggest that in the future investigators should document menstrual cycle phase in all female subjects and, when studying body temperature, should carefully monitor symptomatic state in comparison subjects.
由于黄体后期烦躁障碍（LLPDD）女性会可预测地经历有症状的情感状态，因此可以对她们进行研究，以确定是否存在仅与临床症状状态相关的生物学发现。作者试图回答这个问题：体温会随情感状态而变化吗？
将10名经前综合征（PMS）女性（其中6名也符合LLPDD标准）且无其他心理或医学疾病的核心体温和运动活动模式，与6名患有慢性、非周期性烦躁症的女性以及6名无症状对照女性在月经周期的四个阶段进行比较。
在整个月经周期中，PMS/LLPDD女性的夜间体温显著高于对照受试者，但夜间活动水平没有差异。非周期性烦躁症女性在卵泡期的平均夜间体温与PMS/LLPDD女性一样高。所有女性的体温在黄体期均高于卵泡期。
这些发现表明，未来研究人员应记录所有女性受试者的月经周期阶段，并且在研究体温时，应仔细监测对照受试者的症状状态。
