Lewicky-Gaupp Christina, Wei John T, Delancey John O L, Fenner Dee E, McGuire Edward J, Morgan Daniel M
Pelvic Floor Research Group, Division of Gynecology, Department of Obstetrics and Gynecology, University of Michigan School of Medicine, Ann Arbor, MI, USA.
Am J Obstet Gynecol. 2008 Dec;199(6):680.e1-5. doi: 10.1016/j.ajog.2008.07.027. Epub 2008 Oct 30.
The objective of this study was to establish categories of symptom severity based on Incontinence Symptom Index (ISI) scores and to show how these categories are associated with urethral function and support.
Women with stress incontinence (n = 97) and asymptomatic controls (n = 98) completed the ISI. Asymptomatic women's scores were between 0 and 6; this range was designated as absent/mild (n = 104). The median score for symptomatic women was 16; scores from 7 to 16 (n = 50) were designated as moderate, and scores of 17 or greater (n = 40) were designated as severe.
Urethral function differed in women with mild, moderate, and severe scores: Valsalva leak point pressure (162.3 vs 123.5 vs 101.9 cm H(2)O; P = .001), cough leak point pressure (202.0 vs 163.0 vs 134.3 cm H(2)O; P = .001), and maximum urethral closure pressure (69.1 vs 44.1 vs 35.3 cm H(2)O; P = .001). Loss of urethrovesical support (point Aa: -1.0 vs -0.6 vs -0.5 cm; P = .004) was found in women with moderate and severe symptoms, compared with those with mild symptoms.
Categories of symptom severity assessed by the ISI are associated with urethral function and support.
本研究的目的是根据尿失禁症状指数（ISI）评分建立症状严重程度类别，并展示这些类别与尿道功能及支撑的关联。
压力性尿失禁女性（n = 97）和无症状对照者（n = 98）完成了ISI评估。无症状女性的评分在0至6分之间；该范围被指定为无/轻度（n = 104）。有症状女性的中位数评分为16分；7至16分（n = 50）被指定为中度，17分及以上（n = 40）被指定为重度。
轻度、中度和重度评分的女性尿道功能存在差异：瓦尔萨尔瓦漏尿点压力（162.3对123.5对101.9 cm H₂O；P = .001）、咳嗽漏尿点压力（202.0对163.0对134.3 cm H₂O；P = .001）以及最大尿道闭合压力（69.1对44.1对35.3 cm H₂O；P = .001）。与轻度症状女性相比，中度和重度症状女性存在尿道膀胱支撑缺失（Aa点：-1.0对-0.6对-0.5 cm；P = .004）。
通过ISI评估的症状严重程度类别与尿道功能及支撑相关。
