Nunes Fabio P, Bishop Todd, Prasad Manju L, Madison J Mark, Kim Daniel Y
Department of Medicine, University of Massachusetts, Worcester, Massachusetts 01655, USA.
Laryngoscope. 2008 Nov;118(11):1957-9. doi: 10.1097/MLG.0b013e3181802122.
Isolated laryngeal candidiasis in immunocompetent individuals is a rare entity with fewer than 40 cases reported in the literature. Laryngeal candidiasis secondary to inhaled steroid therapy is usually mild and has been reported in 10% to 15% of patients complaining of dysphonia during treatment. We present a case of laryngeal candidiasis mimicking laryngeal carcinoma in an immunocompetent patient being treated with inhaled fluticasone for chronic obstructive pulmonary disease. Biopsy of the lesion failed to show any signs of malignancy, and patient responded well to oral fluconazole therapy.
免疫功能正常个体中的孤立性喉念珠菌病是一种罕见疾病,文献报道的病例少于40例。吸入性类固醇治疗继发的喉念珠菌病通常较轻,据报道,在治疗期间抱怨声音嘶哑的患者中,有10%至15%出现此病。我们报告一例在使用吸入性氟替卡松治疗慢性阻塞性肺疾病的免疫功能正常患者中,喉念珠菌病酷似喉癌的病例。病变活检未显示任何恶性迹象,患者对口服氟康唑治疗反应良好。