Kiakojuri Keivan, Dehghan Mehdi, Hasanjani Roushan Mohammad Reza, Pourdahash Bijan
Department of Otolaryngology, Babol University of Medical Sciences, Babol, Iran.
Department of Speech Therapy, Babol University of Medical Sciences, Babol, Iran.
Caspian J Intern Med. 2015 Fall;6(4):248-50.
Focal laryngeal candidiasis is not reported widely and is very infrequently recognized clinically. This disease is rare and may occur after pulmonary, pharyngeal and esophageal candidiasis or as part of disseminated disease. It is also secondary to inhaled steroid therapy which is usually mild and has been reported in 10-15 percent of patients taking these medications.
In this study, we introduced a rare case of laryngeal candidiasis in a 79-year-old immunocompromised male presented with 17 months of progressive hoarseness. In video laryngoscopy a white, vegetative mass on anterior one-third of right vocal cord mimicking laryngeal carcinoma. The histopathological examination showed laryngeal mucosal with keratosis, degenerating necrotic epithelial cell aggregates containing hyphea and candida albicans.
In immunocompromised patients, the diagnosis of laryngeal candidiasis should be considered in any patients with laryngeal symptoms.
局灶性喉念珠菌病报道较少，临床很少被识别。这种疾病罕见，可能发生在肺部、咽部和食管念珠菌病之后，或作为播散性疾病的一部分。它也继发于吸入性类固醇治疗，通常症状较轻，在服用这些药物的患者中，有10% - 15%的患者有相关报道。
在本研究中，我们介绍了一例罕见的喉念珠菌病病例，患者为一名79岁免疫功能低下男性，渐进性声音嘶哑17个月。电子喉镜检查发现右侧声带前三分之一处有白色、赘生物样肿物，类似喉癌。组织病理学检查显示喉黏膜有角化病，退变坏死的上皮细胞聚集体中含有菌丝和白色念珠菌。
在免疫功能低下患者中，任何有喉部症状的患者都应考虑喉念珠菌病的诊断。
