Asbury Elizabeth A, Kanji Nasim, Ernst Edzard, Barbir Mahmoud, Collins Peter
Department of Cardiac Medicine, National Heart and Lung Institute, Imperial College London, London, UK.
Menopause. 2009 Jan-Feb;16(1):60-5. doi: 10.1097/GME.0b013e318184762e.
To explore autogenic training (AT) as a treatment for psychological morbidity, symptomology, and physiological markers of stress among women with chest pain, a positive exercise test for myocardial ischemia, and normal coronary arteries (cardiac syndrome X).
Fifty-three women with cardiac syndrome X (mean +/- SD age, 57.1 +/- 8 years) were randomized to an 8-week AT program or symptom diary control. Symptom severity and frequency, Hospital Anxiety and Depression Scale, Spielberger State-Trait Anxiety Inventory, Cardiac Anxiety Questionnaire (CAQ), and Ferrans and Powers Quality of Life Index (QLI), blood pressure, heart rate, electrocardiogram, and plasma catecholamines were measured before and after intervention and at the 8-week follow-up.
Women who underwent AT had improved symptom frequency (8.04 +/- 10.08 vs 1.66 +/- 2.19, P < 0.001) compared with control women and reduced symtom severity (2.08 +/- 1.03 vs 1.23 +/- 1.36, P = 0.02) and frequency (6.11 +/- 3.17 vs 1.66 +/- 2.19, P < G 0.001) post-AT compared with baseline within group. Within-group improvements among women who underwent AT include QLI health functioning (17.80 +/- 5.74 vs 19.41 +/- 5.19, P = 0.04) and CAQ fear (1.53 +/- 0.61 vs 1.35 +/- 0.56, P = 0.02) post-AT and QLI health functioning (17.80 +/- 5.74 vs 20.09 +/- 5.47, P = 0.01), CAQ fear (1.53 +/- 0.61 vs 1.30 +/- 0.67, P = 0.002), CAQ total (1.42 +/- 0.54 vs 1.29 +/- 0.475, P = 0.04), Spielberger State-Trait Anxiety Inventory trait anxiety (42.95 +/- 11.19 vs 38.68 +/- 11.47, P = 0.01), and QLI quality of life (20.67 +/- 5.37 vs 21.9 +/- 4.89, P = 0.02) at follow-up.
An 8-week AT program improves symptom frequency, with near-significant improvements in symptom severity in women with cardiac syndrome X.
探讨自生训练(AT)对胸痛、心肌缺血运动试验阳性且冠状动脉正常(心脏X综合征)女性的心理疾病、症状及应激生理指标的治疗效果。
53名心脏X综合征女性(平均年龄±标准差为57.1±8岁)被随机分为8周的AT训练组或症状日记对照组。在干预前后及8周随访时,测量症状严重程度和频率、医院焦虑抑郁量表、斯皮尔伯格状态-特质焦虑量表、心脏焦虑问卷(CAQ)、费兰斯和鲍尔斯生活质量指数(QLI)、血压、心率、心电图及血浆儿茶酚胺。
与对照组女性相比,接受AT训练的女性症状频率有所改善(8.04±10.08对1.66±2.19,P<0.001),且组内AT训练后与基线相比,症状严重程度降低(2.08±1.03对1.23±1.36,P=0.02),频率降低(6.11±3.17对1.66±2.19,P<0.001)。接受AT训练的女性组内改善包括AT训练后QLI健康功能(17.80±5.74对19.41±5.19,P=0.04)和CAQ恐惧(1.53±0.61对1.35±0.56,P=0.02),随访时QLI健康功能(17.80±5.74对20.09±5.47,P=0.01)、CAQ恐惧(1.53±0.61对1.30±0.67,P=0.002)、CAQ总分(1.42±0.54对1.29±0.475,P=0.04)、斯皮尔伯格状态-特质焦虑量表特质焦虑(42.95±11.19对38.68±11.47,P=0.01)以及QLI生活质量(20.67±5.37对21.9±4.89,P=0.02)。
为期8周的AT训练可改善心脏X综合征女性的症状频率,症状严重程度也有近乎显著的改善。