Institute of Psychosocial Medicine, Psychotherapy and Psychooncology, Jena University Hospital, Stoystr. 3, 07743, Jena, Germany.
University of Applied Health Sciences, Gera, Germany.
Int J Behav Med. 2022 Oct;29(5):531-542. doi: 10.1007/s12529-021-10038-6. Epub 2021 Oct 27.
Autogenic training (AT) is frequently used as therapeutic approach in multimodal pain therapy. The aim of this systematic review and meta-analysis is to investigate the efficacy of AT in individuals suffering from chronic pain in comparison to passive and active control groups.
A comprehensive literature search in Medline, Web of Science, PsycInfo, and PubPsych and manual searches (last search April 7, 2021) were conducted to locate randomized controlled trials (RCTs). Treatment guidelines and references of relevant articles and previous reviews were checked. ProQuest Dissertations and Theses Full Text database, DART-Europe E-theses Portal, Networked Digital Library of Theses and Dissertations (NDLTD), and the Theses Database of the German National Library were screened to identify any unpublished material.
A total of 13 eligible studies (k = 15 comparisons) including 576 participants were identified. Random-effects meta-analyses revealed a significantly positive, moderate effect of AT on the primary outcome pain compared to passive control groups (g = 0.58, 95% CI [0.36; 0.79], k = 9, I = 0%). In comparison with other psychological interventions, no difference was found (g = - 0.05, 95% CI [- 0.30; 0.20], k = 6, I = 0%). Sensitivity analyses proved the robustness of findings. Overall risk-of-bias judgment was 'some concerns' in the majority of studies.
Beneficial effects of AT on pain reduction were demonstrated, but findings are prone to bias. Furthermore, high methodological quality RCTs are needed to strengthen the promising evidence of AT for individuals with chronic pain.
自生训练(AT)常用于多模式疼痛治疗中的治疗方法。本系统评价和荟萃分析的目的是调查 AT 在慢性疼痛个体中的疗效,与被动和主动对照组相比。
在 Medline、Web of Science、PsycInfo 和 PubPsych 中进行全面的文献检索,并进行手动搜索(最后一次搜索时间为 2021 年 4 月 7 日),以定位随机对照试验(RCT)。检查了治疗指南以及相关文章和以前综述的参考文献。还筛选了 ProQuest 学位论文全文数据库、DART-Europe E-theses Portal、Networked Digital Library of Theses and Dissertations (NDLTD) 和德国国家图书馆论文数据库,以确定任何未发表的材料。
共确定了 13 项符合条件的研究(k=15 项比较),包括 576 名参与者。随机效应荟萃分析显示,与被动对照组相比,AT 对主要结局疼痛具有显著的积极、中度影响(g=0.58,95%置信区间[0.36;0.79],k=9,I=0%)。与其他心理干预相比,未发现差异(g=−0.05,95%置信区间[−0.30;0.20],k=6,I=0%)。敏感性分析证明了研究结果的稳健性。大多数研究的总体风险偏倚判断为“存在一些关注”。
证明了 AT 在减轻疼痛方面的有益效果,但研究结果容易出现偏倚。此外,需要高质量的 RCT 来加强 AT 对慢性疼痛个体的有前途的证据。