Cui Lian-Hua, Choi Jin-Su, Shin Min-Ho, Kweon Sun-Seog, Park Kyeong-Soo, Lee Young-Hoon, Nam Hae-Sung, Jeong Seul-Ki, Im Jeong-Soo
Department of Public Health, Qingdao University Medical College, Qingdao, China.
J Bone Miner Metab. 2008;26(6):609-17. doi: 10.1007/s00774-007-0847-8. Epub 2008 Nov 1.
The aims of this study were to establish reference data for bone mineral density (BMD) at central skeletal sites using Lunar dual-energy X-ray absorptiometry (DXA), and to estimate the age-and sex-specific prevalence of osteoporosis in a Korean population. We performed a population-based, cross-sectional study. The subjects were 4148 (1810 men and 2338 women) Korean adults, aged 20-79 years. The BMD for central sites (lumbar spine, femoral neck, trochanter, and Ward's triangle) were measured by DXA. The standardized prevalence of osteoporosis among individual aged 50-79 years in lumbar spine, femoral neck, Ward's triangle, and trochanter was 40.1%, 12.4%, 28.4%, and 4.4% in women and 6.5%, 5.9%, 3.7%, and 1.6% in men, respectively. In women, peak BMD occurred in the age range 40-49 years for the femoral neck and trochanter, 30-39 years for the lumbar spine, and 20-29 years for Ward's triangle. In men, peak BMD values were observed at 20-29 years for all measured sites. This study establishes a normative database for BMD at central skeletal sites using dual-energy X-ray absorptiometry and provides more reliable information on the prevalence of osteoporosis in Korea.
本研究的目的是使用Lunar双能X线吸收法（DXA）建立中轴骨部位骨密度（BMD）的参考数据，并估算韩国人群中按年龄和性别划分的骨质疏松症患病率。我们开展了一项基于人群的横断面研究。研究对象为4148名年龄在20 - 79岁之间的韩国成年人（1810名男性和2338名女性）。通过DXA测量中轴部位（腰椎、股骨颈、大转子和沃德三角）的骨密度。50 - 79岁个体中，腰椎、股骨颈、沃德三角和大转子部位骨质疏松症的标准化患病率在女性中分别为40.1%、12.4%、28.4%和4.4%，在男性中分别为6.5%、5.9%、3.7%和1.6%。在女性中，股骨颈和大转子的骨密度峰值出现在40 - 49岁年龄段，腰椎出现在30 - 39岁年龄段，沃德三角出现在20 - 29岁年龄段。在男性中，所有测量部位的骨密度峰值均出现在20 - 29岁。本研究使用双能X线吸收法建立了中轴骨部位骨密度的标准数据库，并提供了关于韩国骨质疏松症患病率的更可靠信息。
