Department of Emergency, Brugmann University Hospital, Brussels, Belgium.
Clin Appl Thromb Hemost. 2009 Oct;15(5):591-5. doi: 10.1177/1076029608324928. Epub 2008 Nov 2.
A case of an 18-year-old man with deep venous thrombosis of the lower limbs caused by hypoplasia of the inferior vena cava in combination with heterozygous factor V Leiden is presented. Both anomalies were found when the patient complained of venous claudication in both thighs. Inferior vena cava malformation is a rare condition and may predispose to the development of deep venous thrombosis. This patient was at an even higher risk for deep venous thrombosis as the inferior vena cava malformation was combined with a hypercoagulable state.
现报告 1 例 18 岁男性患者，因下腔静脉发育不良合并杂合子因子 V 莱顿突变导致下肢深静脉血栓形成。患者出现双大腿静脉跛行时发现了这两种异常。下腔静脉畸形是一种罕见的疾病，可能易导致深静脉血栓形成。由于下腔静脉畸形合并高凝状态，该患者发生深静脉血栓形成的风险更高。
