长叶刺蒺藜对雄性大鼠性行为的影响。

Effects ofEurycoma longifolia Jack on sexual behaviour of male rats.

作者信息

Ang H H, Sim M K

机构信息

School of Pharmaceutical Sciences, University of Science Malaysia, 11800, Minden, Penang, Malaysia.

出版信息

Arch Pharm Res. 1997 Dec;20(6):656-8. doi: 10.1007/BF02975228.

DOI:10.1007/BF02975228

PMID:18982276

Abstract

The effects ofEurycoma longifolia Jack were studied on the sexual behaviour of male rats. Sexually normal male rats were treated twice daily with 500 mg kg(-1) of different fractions ofE. longifolia Jack for 10 days prior to test and were then observed for their copulatory behaviour with a receptive female in a copulation cage. Results showed that was a significant increase (p<0.05) in EL-1, EL-2, EL-3 but significant decrease (p<0.05) in both PEI-1 and PEI-2 in treated male rats as compared to the control male rats indicating thatE. longifolia Jack increased the sexual performance of the treated male rats by extending the duration of coitus and decreasing the refractory period between the different series of copulation. Hence, this preliminary work supports the folk use of this plant as having aphrodisiac property.

摘要

研究了长叶刺蒺藜对雄性大鼠性行为的影响。在测试前10天，对性正常的雄性大鼠每天两次给予500 mg kg(-1)的长叶刺蒺藜不同部位提取物，然后将其置于交配笼中，观察它们与处于发情期的雌性大鼠的交配行为。结果表明，与对照雄性大鼠相比，接受治疗的雄性大鼠中，EL-1、EL-2、EL-3显著增加（p<0.05），而PEI-1和PEI-2均显著减少（p<0.05），这表明长叶刺蒺藜通过延长性交持续时间和缩短不同交配系列之间的不应期，提高了接受治疗的雄性大鼠的性能力。因此，这项初步研究支持了该植物具有壮阳特性的民间用法。