Hiraoka Kenichiro, Fuchiwaki Megumi, Hiraoka Kaori, Horiuchi Toshitaka, Okano Shinichiro, Kinutani Masayuki, Kinutani Kazuo
Kinutani Women's Clinic, 8-23-4F, Hondori, Naka-ku, Hiroshima 730-0035, Japan.
Reprod Biomed Online. 2008 Nov;17(5):689-94. doi: 10.1016/s1472-6483(10)60317-3.
This case report describes successful pregnancies after vitrification of human day-7 blastocysts. A total of 16 day-7 blastocysts were vitrified and warmed. All 16 blastocysts survived after warming and were transferred to 11 patients. Six of the women (55%) became clinically pregnant and the implantation rate was 44% (7/16). Among these women, one woman delivered a healthy baby, two pregnancies ended in miscarriage, and three pregnancies are ongoing at 10, 29 and 34 weeks of gestation. This is the first report of successful pregnancies after vitrification of human day-7 blastocysts.
本病例报告描述了人类第7天囊胚玻璃化冷冻后成功妊娠的情况。共有16个第7天囊胚被玻璃化冷冻并解冻。解冻后所有16个囊胚均存活,并被移植到11名患者体内。其中6名女性(55%)临床妊娠,着床率为44%(7/16)。在这些女性中,一名女性分娩了一个健康婴儿,两次妊娠以流产告终,还有三次妊娠分别处于妊娠10周、29周和34周且仍在继续。这是关于人类第7天囊胚玻璃化冷冻后成功妊娠的首例报告。