临床试验的途径。
Gateways to clinical trials.
作者信息
Tomillero A, Moral M A
出版信息
Methods Find Exp Clin Pharmacol. 2008 Sep;30(7):543-88.
Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug discovery and development portal, http://integrity.prous.com.This issue focuses on the following selection of drugs: ABT-263, AC-2307, Aclidinium bromide, Adefovir dipivoxil, ADH-1, Agatolimod sodium, Alefacept, Aliskiren fumarate, Aminolevulinic acid methyl ester, Anakinra, Apaziquone, Aprepitant, Aripiprazole, ASM-8, Atiprimod hydrochloride, AVE-0277, AVE-1642, AVE-8062, Axitinib, Azacitidine, AZD-0530; Bazedoxifene acetate, Bevacizumab, Bexarotene, BI-2536, Biphasic insulin aspart, BMS-387032, BMS-663513, Bortezomib, BQ-123, Brivanib alaninate, BSI-201; Caspofungin acetate, CDX-110, Cetuximab, Ciclesonide, CR-011, Cypher; Daptomycin, Darbepoetin alfa, Dasatinib, Decitabine, Deferasirox, Denosumab, Dexlansoprazole, Dexmethylphenidate hydrochloride, DNA-Hsp65 vaccine, Dovitinib, Drotrecogin alfa (activated), DTaP-HBV-IPV/Hibvaccine, DTaP-IPV-HB-PRP-T, Duloxetine hydrochloride, Dutasteride; Ecogramostim, Elacytarabine, Emtricitabine, Endothelin, Entecavir, Eplivanserin fumarate, Escitalopram oxalate, Everolimus, Ezetimibe, Ezetimibe/simvastatin; Farletuzumab, Fesoterodine fumarate, Fibrin sealant (human), Fulvestrant; Gefitinib, Gemtuzumab ozogamicin, Glufosfamide, GSK-1562902A; Hib-TT; Imatinib mesylate, IMC-11F8, Imidazoacridinone, IMP-321, INCB-18424, Indiplon, Indisulam, INNO-406, Irinotecan hydrochloride/Floxuridine, ITF-2357, Ixabepilone; KRN-951; Lasofoxifene tartrate; Lenalidomide, LGD-4665, Lonafarnib, Lubiprostone, Lumiliximab; MDX-1100, Melan-A/MART-1/gp100/IFN-alfa, Methyl-CDDO, Metreleptin, MLN-2704, Mycophenolic acid sodium salt; Na-ASP-2, Naproxcinod, Nilotinib hydrochloride monohydrate, NPI-2358; Oblimersen sodium, Odanacatib; Paclitaxel nanoparticles, PAN-811, Panobinostat, PBI-1402, PC-515, Peginterferon alfa-2a, Peginterferon alfa-2b, Pemetrexed disodium, Perillyl alcohol, Perphenazine 4-aminobutyrate, PeviPRO/breast cancer, PF-03814735, PHA-739358, Pimecrolimus, Plitidepsin, Posaconazole, Prasterone, Prasugrel, Pregabalin, Prucalopride, PRX-08066; rAAV2-TNFR:Fc, Ranelic acid distrontium salt, Ranibizumab, rCD154-CLL, Retapamulin, RTS,S/SBAS2, rV-PSA-TRICOM/rF-PSA-TRICOM; SG-2000, Sinecatechins, Sirolimus-eluting stent, Sorafenib, SP-1640, Strontium malonate, Succinobucol, Sunitinib malate; Taxus, Teduglutide, Telavancin hydrochloride, Telbivudine, Telmisartan/hydrochlorothiazide, Tenofovir disoproxil fumarate, Tenofovir disoproxil fumarate/emtricitabine, Tocilizumab; Ustekinumab; V-5 Immunitor, Voriconazole, Vorinostat; Xience V, XL-184, XL-647, XL-765; Y-39983, Zibotentan.
《临床试验指南》是当前文献和会议中最新临床试验的指南。以下表格中的数据取自药物研发门户网站Prous Science Integrity的临床试验知识领域，网址为http://integrity.prous.com 。本期重点关注以下药物：ABT - 263、AC - 2307、阿地溴铵、阿德福韦酯、ADH - 1、阿加托莫德钠、阿来西普、富马酸阿利吉仑、氨基乙酰丙酸甲酯、阿那白滞素、阿帕醌、阿瑞匹坦、阿立哌唑、ASM - 8、盐酸阿替莫德、AVE - 0277、AVE - 1642、AVE - 8062、阿昔替尼、阿扎胞苷、AZD - 0530；醋酸巴多昔芬、贝伐单抗、贝沙罗汀、BI - 2536、双相门冬胰岛素、BMS - 387032、BMS - 663513、硼替佐米、BQ - 123、布立尼布丙氨酸盐、BSI - 201；醋酸卡泊芬净、CDX - 110、西妥昔单抗、环索奈德、CR - 011、西罗莫司洗脱支架；达托霉素、聚乙二醇化促红细胞生成素α、达沙替尼、地西他滨、地拉罗司、地诺单抗、右兰索拉唑、盐酸右甲基苯丙胺、DNA - Hsp65疫苗、多韦替尼、活化蛋白C、DTaP - HBV - IPV/Hib疫苗、DTaP - IPV - HB - PRP - T、盐酸度洛西汀、度他雄胺；生态粒细胞刺激因子、依拉胞苷、恩曲他滨、内皮素、恩替卡韦、富马酸依普利凡塞、草酸艾司西酞普兰、依维莫司、依折麦布、依折麦布/辛伐他汀；法乐妥珠单抗、富马酸非索罗定、人纤维蛋白封闭剂、氟维司群；吉非替尼、吉妥单抗、葡磷酰胺、GSK - 1562902A；Hib - TT；甲磺酸伊马替尼、IMC - 11F8、咪唑吖啶酮、IMP - 321、INCB - 18424、茚地普隆、茚苏拉姆、INNO - 406、盐酸伊立替康/氟尿苷、ITF - 2357、伊沙匹隆；KRN - 951；酒石酸拉索昔芬；来那度胺、LGD - 4665、洛那法尼、鲁比前列酮、鲁米利昔单抗；MDX - 1100、黑色素瘤抗原A/MART - 1/gp100/干扰素α、甲基 - CDDO、美曲普明、MLN - 2704、霉酚酸钠盐；Na - ASP - 2、萘普生辛、盐酸尼罗替尼一水合物、NPI - 2358；奥布利默森钠、奥达卡替；紫杉醇纳米粒、PAN - 811、帕比司他、PBI - 1402、PC - 515、聚乙二醇化干扰素α - 2a、聚乙二醇化干扰素α - 2b、培美曲塞二钠、紫苏醇、奋乃静4 - 氨基丁酸盐、PeviPRO/乳腺癌、PF - 03814735、PHA - 739358、吡美莫司、普利替地辛、泊沙康唑、普拉睾酮、普拉格雷、普瑞巴林、普芦卡必利、PRX - 08066；重组腺相关病毒2 - TNFR:Fc、雷尼酸锶盐、雷珠单抗、rCD154 - CLL、瑞他帕林、RTS,S/SBAS2、重组痘苗病毒 - PSA - TRICOM/重组流感病毒 - PSA - TRICOM；SG - 2000、表儿茶素、西罗莫司洗脱支架、索拉非尼、SP - 1640、丙二酸锶、琥珀酸布可、苹果酸舒尼替尼；红豆杉、替度鲁肽、盐酸特拉万星、替比夫定、替米沙坦/氢氯噻嗪、富马酸替诺福韦二吡呋酯、富马酸替诺福韦二吡呋酯/恩曲他滨、托珠单抗；乌司奴单抗；V - 5免疫抑制剂、伏立康唑、伏立诺他；Xience V、XL - 184、XL - 647、XL - 765；Y - 39983、齐博坦。
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