Lew Bark-Lynn, Shin Min-Kyung, Sim Woo-Young
Department of Dermatology, College of Medicine, Kyunghee University, Seoul, Korea.
J Am Acad Dermatol. 2009 Jan;60(1):85-93. doi: 10.1016/j.jaad.2008.08.045. Epub 2008 Nov 6.
Alopecia areata (AA) appears in several clinical forms, all having different clinical courses and different prognoses. Acute diffuse and total alopecia (ADTA) has been reported to have a short clinical course ranging from acute hair loss to total baldness, followed by rapid recovery.
To determine the clinical course and prognosis of ADTA through precise clinical observations.
Thirty Korean patients who showed ADTA of the scalp within an average of 10 weeks after the onset of hair loss were studied.
Most patients were women who were older than 20 years of age. The histopathology of the lesion revealed infiltration of mononuclear cells around the hair follicles and prominent pigment incontinence. The patients experienced hair regrowth within about 6 months, without regard to the method of treatment.
The duration of follow-up after remission ranged from 3 to 49 months, with a mean of 24 months.
These cases can be categorized as having "acute diffuse and total alopecia," a new subtype of AA that is associated with a favorable prognosis and rapid and spontaneous recovery even without treatment.
斑秃（AA）有多种临床形式，其临床病程和预后各不相同。急性弥漫性全秃（ADTA）据报道临床病程较短，从急性脱发到全秃，随后迅速恢复。
通过精确的临床观察确定ADTA的临床病程和预后。
对30例韩国患者进行研究，这些患者在脱发开始后平均10周内出现头皮ADTA。
大多数患者为20岁以上的女性。病变的组织病理学显示毛囊周围有单核细胞浸润和明显的色素失禁。无论治疗方法如何，患者在约6个月内头发再生。
缓解后的随访时间为3至49个月，平均24个月。
这些病例可归类为“急性弥漫性全秃”，这是斑秃的一种新亚型，预后良好，即使未经治疗也能迅速自发恢复。
