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斑秃的毛发镜检查模式:系统评价和荟萃分析。

Trichoscopy pattern in alopecia areata: A systematic review and meta-analysis.

机构信息

Department of Dermatology, College of Medicine, Shaqra University, Dawadmi, Saudi Arabia.

Division of Dermatology, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.

出版信息

Skin Res Technol. 2023 Jun;29(6):e13378. doi: 10.1111/srt.13378.

DOI:10.1111/srt.13378
PMID:37357664
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10236002/
Abstract

BACKGROUND

The incidence of alopecia areata (AA) has increased over the last few decades. Trichoscopy is a noninvasive procedure performed in dermatology clinics and is a helpful tool in determining the correct diagnosis of hair loss presentations.

OBJECTIVE

Through mapping the researches that have been done to represent the spectrum of trichoscopic findings in AA and to identify the most characteristic patterns.

METHODS

Thirty-nine studies were eligible for the quantitative analysis. Meta-analysis and subgroup analysis were performed.

RESULTS

Thirty-nine studies (29 cross-sectional, five retrospective, two descriptive, one case series, one observational, and one cohort) with a total of 3204 patients were included. About 66.7% of the studies were from Asia, 25.6% from Europe, and 7.7% from Africa. The most characteristic trichoscopic findings of AA were as follows; yellow dots, black dots, broken hairs, short vellus hairs, and tapering hairs.

CONCLUSION

There is no single pathognomonic diagnostic trichoscopic finding in AA rather than a constellation of characteristic findings. The five most characteristic trichoscopic findings in AA are: yellow dots, black dots, broken hairs, short vellus hairs, and tapering hairs. Yellow dots and short vellus hairs considered the most sensitive clues for AA, while black dots and tapering hairs are the most specific ones. Furthermore, trichoscopy is a useful tool that allows monitoring of response during the treatment of AA. Treatment responded cases will show an increase in short vellus hairs, but loss of tapering hairs, broken hairs, and black dots, while yellow dots are the least responsive to the treatment.

摘要

背景

斑秃(AA)的发病率在过去几十年中有所增加。皮肤镜检查是皮肤科中进行的一种非侵入性操作,是确定脱发表现正确诊断的有用工具。

目的

通过绘制已完成的研究,以代表 AA 的皮肤镜检查结果谱,并确定最具特征性的模式。

方法

有 39 项研究符合定量分析的条件。进行了荟萃分析和亚组分析。

结果

共纳入 39 项研究(29 项横断面研究、5 项回顾性研究、2 项描述性研究、1 项病例系列研究、1 项观察性研究和 1 项队列研究),共 3204 例患者。约 66.7%的研究来自亚洲,25.6%来自欧洲,7.7%来自非洲。AA 最具特征性的皮肤镜检查结果如下:黄点、黑点、断发、毳毛和变细发。

结论

AA 没有单一的特异性皮肤镜检查发现,而是一系列特征性发现。AA 中最具特征性的 5 种皮肤镜检查结果是:黄点、黑点、断发、毳毛和变细发。黄点和毳毛被认为是 AA 最敏感的线索,而黑点和变细发则是最具特异性的线索。此外,皮肤镜检查是一种有用的工具,可用于监测 AA 治疗过程中的反应。治疗有反应的病例将显示短毳毛增加,但变细发、断发和黑点减少,而黄点对治疗的反应最小。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3012/10236002/a5a4d1c93acc/SRT-29-e13378-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3012/10236002/b547f6246590/SRT-29-e13378-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3012/10236002/bcb998ce15f6/SRT-29-e13378-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3012/10236002/bf05173e0731/SRT-29-e13378-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3012/10236002/7e734089e109/SRT-29-e13378-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3012/10236002/f673508a5c5d/SRT-29-e13378-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3012/10236002/f92ead66e92a/SRT-29-e13378-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3012/10236002/a5a4d1c93acc/SRT-29-e13378-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3012/10236002/b547f6246590/SRT-29-e13378-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3012/10236002/bcb998ce15f6/SRT-29-e13378-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3012/10236002/bf05173e0731/SRT-29-e13378-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3012/10236002/7e734089e109/SRT-29-e13378-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3012/10236002/f673508a5c5d/SRT-29-e13378-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3012/10236002/f92ead66e92a/SRT-29-e13378-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3012/10236002/a5a4d1c93acc/SRT-29-e13378-g001.jpg

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