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miRecords: an integrated resource for microRNA-target interactions.

作者信息

Xiao Feifei, Zuo Zhixiang, Cai Guoshuai, Kang Shuli, Gao Xiaolian, Li Tongbin

机构信息

Department of Neuroscience, University of Minnesota, Minneapolis, MN 55455, USA.

出版信息

Nucleic Acids Res. 2009 Jan;37(Database issue):D105-10. doi: 10.1093/nar/gkn851. Epub 2008 Nov 7.


DOI:10.1093/nar/gkn851
PMID:18996891
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2686554/
Abstract

MicroRNAs (miRNAs) are an important class of small noncoding RNAs capable of regulating other genes' expression. Much progress has been made in computational target prediction of miRNAs in recent years. More than 10 miRNA target prediction programs have been established, yet, the prediction of animal miRNA targets remains a challenging task. We have developed miRecords, an integrated resource for animal miRNA-target interactions. The Validated Targets component of this resource hosts a large, high-quality manually curated database of experimentally validated miRNA-target interactions with systematic documentation of experimental support for each interaction. The current release of this database includes 1135 records of validated miRNA-target interactions between 301 miRNAs and 902 target genes in seven animal species. The Predicted Targets component of miRecords stores predicted miRNA targets produced by 11 established miRNA target prediction programs. miRecords is expected to serve as a useful resource not only for experimental miRNA researchers, but also for informatics scientists developing the next-generation miRNA target prediction programs. The miRecords is available at http://miRecords.umn.edu/miRecords.

摘要

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本文引用的文献

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[2]
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