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通过硼酸衍生化提高离子淌度-质谱分析中的碳水化合物结构选择性

Enhanced carbohydrate structural selectivity in ion mobility-mass spectrometry analyses by boronic acid derivatization.

作者信息

Fenn Larissa S, McLean John A

机构信息

Department of Chemistry and Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37235, USA.

出版信息

Chem Commun (Camb). 2008 Nov 21(43):5505-7. doi: 10.1039/b810421b. Epub 2008 Sep 22.

DOI:10.1039/b810421b
PMID:18997933
Abstract

The boronic acid derivatization of carbohydrates is demonstrated as an ion mobility shift strategy to improve confidence in the identification and characterization of carbohydrate assignments using ion mobility-mass spectrometry.

摘要

碳水化合物的硼酸衍生化被证明是一种离子迁移率偏移策略，可提高使用离子迁移率-质谱法对碳水化合物归属进行鉴定和表征的可信度。

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