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High-density cultivation of insect cells and production of recombinant baculovirus using a novel oscillating bioreactor.新型振荡生物反应器高密度培养昆虫细胞和生产重组杆状病毒。
Cytotechnology. 2003 Sep;42(3):145-53. doi: 10.1023/B:CYTO.0000015841.98225.27.
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Japanese encephalitis virus production in Vero cells with serum-free medium using a novel oscillating bioreactor.使用新型振荡生物反应器在无血清培养基的Vero细胞中生产日本脑炎病毒
Biologicals. 2007 Oct;35(4):221-6. doi: 10.1016/j.biologicals.2007.02.002. Epub 2007 Apr 2.
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A novel oscillating bioreactor BelloCell: implications for insect cell culture and recombinant protein production.一种新型振荡生物反应器BelloCell：对昆虫细胞培养和重组蛋白生产的影响。
Biotechnol Lett. 2005 Aug;27(15):1059-65. doi: 10.1007/s10529-005-8450-3.
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Combination of baculovirus-mediated gene delivery and packed-bed reactor for scalable production of adeno-associated virus.杆状病毒介导的基因递送与填充床反应器相结合用于腺相关病毒的规模化生产。
Hum Gene Ther. 2007 Nov;18(11):1161-70. doi: 10.1089/hum.2007.107.
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Baculovirus-mediated production of HDV-like particles in BHK cells using a novel oscillating bioreactor.利用新型振荡生物反应器在BHK细胞中通过杆状病毒介导生产丁型肝炎病毒样颗粒。
J Biotechnol. 2005 Aug 4;118(2):135-47. doi: 10.1016/j.jbiotec.2005.02.018.
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Pseudorabies virus production using a serum-free medium in fixed-bed bioreactors with low cell inoculum density.在固定床生物反应器中使用无血清培养基以低细胞接种密度生产伪狂犬病病毒。
Biotechnol Lett. 2020 Dec;42(12):2551-2560. doi: 10.1007/s10529-020-02987-x. Epub 2020 Aug 20.
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Insect cell entrapment, growth and recovering using a single-use fixed-bed bioreactor. Scaling up and recombinant protein production.使用一次性固定床生物反应器进行昆虫细胞包埋、生长及回收。放大培养及重组蛋白生产。
J Biotechnol. 2015 Dec 20;216:110-5. doi: 10.1016/j.jbiotec.2015.10.013. Epub 2015 Oct 23.
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Perfluorocarbon-mediated aeration applied to recombinant protein production by virus-infected insect cells.全氟碳介导的通气应用于病毒感染昆虫细胞生产重组蛋白。
Biochem Eng J. 2001 Jan;7(1):69-78. doi: 10.1016/s1369-703x(00)00103-0.
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Optimal production of recombinant protein by the baculovirus-insect cell system in shake-flask culture with medium replacement.通过杆状病毒-昆虫细胞系统在摇瓶培养中更换培养基来优化重组蛋白的生产。
J Biosci Bioeng. 1999;87(5):636-41. doi: 10.1016/s1389-1723(99)80127-3.
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A novel control scheme for inducing angiostatin-human IgG fusion protein production using recombinant CHO cells in a oscillating bioreactor.一种在振荡生物反应器中使用重组CHO细胞诱导血管抑素-人IgG融合蛋白产生的新型控制方案。
J Biotechnol. 2006 Feb 10;121(3):418-28. doi: 10.1016/j.jbiotec.2005.07.025. Epub 2005 Sep 12.
引用本文的文献
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The diverse metabolic heterogeneity of stem cells in a BRCA+/-breast cancer population.BRCA+/- 乳腺癌人群中干细胞的代谢异质性。
J Med Life. 2021 May-Jun;14(3):331-336. doi: 10.25122/jml-2020-0105.
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Production of small ruminant morbillivirus, rift valley fever virus and lumpy skin disease virus in CelCradle™ -500A bioreactors.在 CelCradle™ -500A 生物反应器中生产小反刍兽疫病毒、裂谷热病毒和牛结节性皮肤病病毒。
BMC Vet Res. 2021 Feb 27;17(1):93. doi: 10.1186/s12917-021-02801-4.
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Evaluation of novel disposable bioreactors on pandemic influenza virus production.新型一次性生物反应器在大流行流感病毒生产中的评估。
PLoS One. 2019 Aug 12;14(8):e0220803. doi: 10.1371/journal.pone.0220803. eCollection 2019.
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Cultivation of HEK 293 cell line and production of a member of the superfamily of G-protein coupled receptors for drug discovery applications using a highly efficient novel bioreactor.HEK293 细胞系的培养和使用高效新型生物反应器生产 G 蛋白偶联受体超家族成员，用于药物发现应用。
Cytotechnology. 2004 Jul;45(3):117-23. doi: 10.1007/s10616-004-6402-8.
本文引用的文献
1
Disposable bioreactor for cell culture using wave-induced agitation.采用波激震荡搅拌的一次性细胞培养生物反应器。
Cytotechnology. 1999 Jul;30(1-3):149-58. doi: 10.1023/A:1008025016272.
2
Continuous production and recovery of recombinant Ca2+ binding receptor from HEK 293 cells using perfusion through a packed bed bioreactor.使用填充床生物反应器连续生产和从 HEK 293 细胞中回收重组 Ca2+ 结合受体。
Cytotechnology. 2000 Jul;33(1-3):3-11. doi: 10.1023/A:1008143132056.
3
Effect of elevated oxygen and glutamine levels on foreign protein production at high cell densities using the insect cell-baculovirus expression system.利用昆虫细胞-杆状病毒表达系统，研究高氧和谷氨酰胺水平对高细胞密度下外源蛋白生产的影响。
Biotechnol Bioeng. 1997 Apr 20;54(2):142-52. doi: 10.1002/(SICI)1097-0290(19970420)54:2<142::AID-BIT6>3.0.CO;2-L.
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Microcarrier culture of lepidopteran cell lines: implications for growth and recombinant protein production.鳞翅目细胞系的微载体培养：对生长和重组蛋白生产的影响
Biotechnol Prog. 2002 Nov-Dec;18(6):1345-55. doi: 10.1021/bp0255107.
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Fabrication and use of a transient contractional flow device to quantify the sensitivity of mammalian and insect cells to hydrodynamic forces.用于量化哺乳动物细胞和昆虫细胞对流体动力敏感性的瞬态收缩流装置的制造与应用。
Biotechnol Bioeng. 2002 Nov 20;80(4):428-37. doi: 10.1002/bit.10387.
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Characterization of cell-surface determinants important for baculovirus infection.对杆状病毒感染重要的细胞表面决定簇的特征分析。
Virology. 2001 Jan 5;279(1):343-53. doi: 10.1006/viro.2000.0699.
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Production of HIV-1 gp120 in packed-bed bioreactor using the vaccinia virus/T7 expression system.使用痘苗病毒/T7表达系统在填充床生物反应器中生产HIV-1 gp120。
Biotechnol Prog. 2000 Sep-Oct;16(5):744-50. doi: 10.1021/bp000112u.
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Gas exchange is essential for bioreactor cultivation of tissue engineered cartilage.气体交换对于组织工程软骨的生物反应器培养至关重要。
Biotechnol Bioeng. 1999 Apr 20;63(2):197-205. doi: 10.1002/(sici)1097-0290(19990420)63:2<197::aid-bit8>3.0.co;2-2.
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Use of a hollow fiber bioreactor for large-scale production of alpha 2-adrenoceptors in mammalian cells.使用中空纤维生物反应器在哺乳动物细胞中大规模生产α2肾上腺素能受体。
J Biotechnol. 1994 Sep 30;37(2):179-84. doi: 10.1016/0168-1656(94)90009-4.
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Production of human alkaline phosphatase, a secreted, glycosylated protein, from a baculovirus expression system and the attachment-dependent cell line Trichoplusia ni BTI-Tn 5B1-4 using a split-flow, air-lift bioreactor.使用分流式气升生物反应器，从杆状病毒表达系统和依赖贴壁的细胞系草地贪夜蛾BTI-Tn 5B1-4中生产人碱性磷酸酶，这是一种分泌型糖蛋白。
Biotechnol Prog. 1993 Nov-Dec;9(6):675-8. doi: 10.1021/bp00024a018.
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