Kerr Ryan J S, Player Gray, Fiscus Susan A, Nelson Julie A E
Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, 11-141 Lineberger Cancer Center, CB 7295, Chapel Hill, NC 27599, USA.
J Clin Microbiol. 2009 Jan;47(1):220-2. doi: 10.1128/JCM.01521-08. Epub 2008 Nov 12.
The Gen-Probe Aptima human immunodeficiency virus type 1 (HIV-1) RNA assay was adapted for the diagnosis of HIV infection in infants by using dried blood spots. The assay was 99% sensitive (128/129) and 100% specific (162/162). This may prove useful in resource-limited settings, since it precludes the need for a phlebotomist and maintenance of a cold chain.
Gen-Probe Aptima 1型人类免疫缺陷病毒(HIV-1)RNA检测方法经调整后,可用于通过干血斑诊断婴儿的HIV感染。该检测方法的灵敏度为99%(128/129),特异性为100%(162/162)。这在资源有限的环境中可能会很有用,因为它无需采血技师,也无需冷链维护。