用于诊断婴儿感染的干血斑的定性人类免疫缺陷病毒RNA分析。
Qualitative human immunodeficiency virus RNA analysis of dried blood spots for diagnosis of infections in infants.
作者信息
Kerr Ryan J S, Player Gray, Fiscus Susan A, Nelson Julie A E
机构信息
Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, 11-141 Lineberger Cancer Center, CB 7295, Chapel Hill, NC 27599, USA.
出版信息
J Clin Microbiol. 2009 Jan;47(1):220-2. doi: 10.1128/JCM.01521-08. Epub 2008 Nov 12.
Abstract
The Gen-Probe Aptima human immunodeficiency virus type 1 (HIV-1) RNA assay was adapted for the diagnosis of HIV infection in infants by using dried blood spots. The assay was 99% sensitive (128/129) and 100% specific (162/162). This may prove useful in resource-limited settings, since it precludes the need for a phlebotomist and maintenance of a cold chain.
摘要
Gen-Probe Aptima 1型人类免疫缺陷病毒（HIV-1）RNA检测方法经调整后，可用于通过干血斑诊断婴儿的HIV感染。该检测方法的灵敏度为99%（128/129），特异性为100%（162/162）。这在资源有限的环境中可能会很有用，因为它无需采血技师，也无需冷链维护。
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